Happy SysAdminDay to all SysAdmins!!! :-) @dwmtwz The Nogales Lab

CasΦ is out! Check it out: nature.com/articles/s4159… Pleasure to work with you guys! @patrick_pausch, K. Soczek, Connor Tsuchida, Basem Al-Shayeb, Ph.D. 🧬, The Banfield Lab, The Nogales Lab, Doudna Lab, #cryoEM

We had fun tuning into #moet2021 with our friends from Berkeley! Thanks to the organizers The Nogales Lab Jane Mellor and Mike Levine for a great virtual meeting!

Cryo-EM of nucleosome phase separation! Awesome work! :-) The Bustamante Lab biorxiv.org/content/10.110…

Wow :D ... I just noticed that my former internet provider in #Switzerland now offers 25gbit/s fiber internet for cheap ... Here you are happy if you get 1 gbit ... who has a router at home that can keep up with that?

Happy to share my first first-author paper with the world! Thx to all my colleagues/friends for their amazing help! Karolin Berneiser Francesca Mangia Stefan Imseng Edward Stuttfeld See here how #DEPTOR functions....

Can you fly protein complexes through native mass-spec, land them on EM grids and solve structures from them? Yes - you can! Here is recent work in collaboration with Coon Lab showing our preliminary NS results. Hopeful for cryo grids soon! biorxiv.org/content/10.110…

If you have a computational background and an interest in working with a very diverse, fun and creative group of people at the frontier of structural biology please consider applying for this position! We are looking for a SysAdmin/IT specialist. tinyurl.com/49ew54n9

Finally hSAGA is out! Thanks to everyone involved! Meagan Esbin The Nogales Lab Also in the HHMI news: hhmi.org/news/surprisin… nature.com/articles/s4159…

#cryoEM structure of the human SAGA complex reveals high-res details of core and TRRAP modules. Work by @Nogaleslab UC Berkeley MCB Berkeley Biophysics LBNL BioSci Tjian + Darzacq Group nature.com/articles/s4159…

Congrats Benjamin LaFrance awesome structure :-) nature.com/articles/s4159…

Someone moved in the bird house that I built for my mother's birthday :-) Raspberry Pi youtu.be/zR-n4JCilmQ

Congratulations to Eva and all the other new fellows from UC Berkeley! news.berkeley.edu/2022/01/26/aaa…

Microsecond laser melting and revitrification of cryo-EM samples does not damage proteins but might improve protein resolution. It also opens the door to plethora of time-resolved biological experiments. biorxiv.org/content/10.110…

New preprint💫(and my first tweet…) This competitive binding using #AlphaFold from @DeepMind idea somehow came to my mind during a discussion with Alberto Perez and arup mondal on related topics and I told them, “I got a weird idea.” 🧵 biorxiv.org/content/10.110…

Hatching day in my mother's nesting box!!! :-) youtube.com/watch?v=TdOmuK…

The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants go.nature.com/3B3oYaZ

High speed X-ray video: jumping beans, wind-up toys and more! youtu.be/xdpDd7dyU00 via YouTube

What is the organization of a #PolyketideSynthase assembly line ? #CryoEM studies of a filament of a trans-AT PKS bimodule core provide a first glimpse at multimodular PKS: science.org/doi/10.1126/sc…