Easy to miss! ⚠️ What's happening here? More pics, immunostains & answer: kikoxp.com/posts/24795 More posts from Dr. Diego Morales, MD kikoxp.com/diego_morales1 #medTwitter #pathology #pathologists #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter

PRAME expression in a cutaneous metastasis of HER2+ breast carcinoma. Some studies (i.e. PMID: 31869767) have reported ⬆️ detection of PRAME in the HER2+ variant of breast CA. It has been correlated with worse prognosis & ⬇️ patient survival. #PathTwitter #dermpath #patologia

Is this #TooCloseToDiagnose ? What is the #ihc stain? Double challenge for #PathTwitter peeps. #ihcpath #dermpath

PRAME expression in myofibroblasts of a scar in an excision of melanocytic lesion, a potential pitfall. Reported last year for the 1st time in this letter to the editor pubmed.ncbi.nlm.nih.gov/35103337/, and this case is a first for me. #PathTwitter #dermpath #ihcpath

80s♂️forehead, RO BCC Who can guess the dx and IHC?⭐️ #dermpath Tim McCalmont Henry YANG Van-Hung Nguyen MD 🇺🇦🌻 Diego Morales, MD Steven Lorand Kis Gonzalo De Toro Daniel Gonzalez, MD Marcelasaeblima. Etan Marks, DO Olaleke Folaranmi Allison Osmond MD MSc FRCPC 🕊 🌎 🕊 @Vollkorntutgut vincenzopolizzi Anurag Sharma Chau Bui Pembe Oltulu, MD

75yo♂️posterior thigh, RO SCCKA I suspect this is one of Henry YANG's favorite diagnoses 猪角斑病? #dermpath Tim McCalmont Diego Morales, MD Anurag Sharma Matthew Cecchini MD PhD FRCPC Christine J. Ko, MD @sarcomapathdoc Dermpath_doc_trish Etan Marks, DO vincenzopolizzi @ArjunRamaiya1 David Terrano Julia P Low Marcelasaeblima.

1/2. Teen♂️Face Looks like a Spitz nevus to me. P16 uniformly retained. Question: Do you give an excision recommendation on your report? If yes, how many millimeters, or just generic excise NOS? Tim McCalmont Henry YANG Arnaud de la Fouchardiere MD, PhD Diego Morales, MD Christine J. Ko, MD Steven

70s♂️scalp RO Pilar Cyst Something we don't see everyday, especially at this site (scalp) #dermpath Tim McCalmont Henry YANG James Sampson Woo Cheal Cho, MD Viral Bhanvadia Gonzalo De Toro Dan Graham Dermpath_doc_trish Olaleke Folaranmi Christine J. Ko, MD Diego Morales, MD @ArjunRamaiya1 Van-Hung Nguyen MD 🇺🇦🌻

The "Eyeliner Sign" in melanoma! While the #EyelinerSign is often linked with SCC in situ/Bowen’s disease or occasionally Paget’s, this case of nevoid (nested) melanoma in situ is showcasing the same distinctive feature. #DermPath #PathTwitter #pathfulness

A “floating nest” Ring-like cleft around a nevus nest. In nevi, they are mostly -but not exclusively- seen in Spitz tribe. Also, clefts have been proposed as a adjuvant clue for a dx of melanoma (Bernie’s Clue 34). #dermpath #pathtwitter #tooprettynottoshare

A sort of pseudo-#EyelinerSign, focal finding in a superficial basal cell carcinoma showing some intraepidermally located nests above the dermoepidermal junction. The IHC is BerEp4. #dermpath #pathtwitter #tooprettynottoshare #pathfulness #freudeandermorphologie

This epidermal mitosis seems appropriate for today’s date. #JoyForMorfology #freudeandermorphologie #tooprettynottoshare #histobeauty #reallifedermpath #dermpath

A mí nadie me dice que debo decir. #dermatopatología🔬💕 #REVIVE2024 msldermatopato.com