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Extremely happy to share this preprint led by Callum Henfrey where we looked at the effects of RNA processing efficiency and chromatin retention on the production of mature mRNAs. biorxiv.org/content/10.110…

We have another funded #PhD project from University of Leicester on protein phosphorylation at the intersection of transcription and DNA repair! Deadline on 20th January 2023. Feel free to contact me if interested! findaphd.com/phds/project/c…

Continuing on the theme of targeting Gene Regulation in cancer, I'm happy to report we're releasing a study today on co-targeting key transcriptional CDKs, CDK12 & P-TEFb, which promote Pol II elongation and have emerged as prominent players in cancer. 1/7 biorxiv.org/content/10.110…

Happy to share our group's newest work! Here, we review the history & current understanding of 7SK RNA/RNP structure and assembly. Congratulations to Momodou and Amr M. Sobeh ! frontiersin.org/articles/10.33…

Amazing retreat of our #MCD lab in the Pyrénées… great talks, great fun! Thanks nomo 🤩🥳

Excited to share this tremendous team’s work on CDK13! Thanks to everyone who made this possible! Dr. Len Zon, Paul Boutz, Phil Sharp, Richard Young, AdelmanLab, Matthias Geyer, @NCIChanock, @kbrowngenetics, Brian J. Abraham, David Liu, Ben Martin, Tongwu Zhang doi.org/10.1126/scienc…

Happy and grateful that I'm starting my own research group, "Developmental Regulation of Gene Dosage", CBI Toulouse 🧬🐹🧫🧪 thanks to an installation grant Fondation pour la Recherche Médicale, a @INSB_CNRS position, and support from the many good mentors and mentees I'm lucky to have ✨ #Xploring

#transcription #Pol II #CTD Transcription without CTD (almost) never ends Happy to share our latest research on Pol II CTD doi.org/10.15252/embr.…

We are hiring!! An ANR-funded PhD position is available in our lab to study regulation of transcription during neuronal differentiation. Join us in Toulouse! CBI Toulouse ANR - Agence nationale de la recherche To apply : emploi.cnrs.fr/Offres/Doctora… Please RT, deadline on 3rd September 2023

📯 Our work on a new core splicing factor is out in Molecular Cell! FUBP1 is important for splicing of long introns. Multivalent interactions support spliceosome assembly and intron bridging. Great collab with @Sattler_lab & Luck_lab. Check it out here: bit.ly/4552p18

Join us! A postdoc position between my lab and Quezada Lab has become available at UCL Cancer Institute in London. Please help us characterise the molecular mechanisms through which anti-tumour immune responses are controlled. To apply ucl.ac.uk/work-at-ucl/se… Deadline 14 Sept Please RT!

What happens when a CDK moves out of their lane? Our review on the overlap between cell-cycle and transcriptional CDKs is out now! Wiley Interdisciplinary Reviews wires.onlinelibrary.wiley.com/doi/10.1002/wr…

Are promoters just landing pads for the transcriptional machinery? No! They can be key regulatory centers during development. Vivek Ramalingam shows this in some beautiful new work published in Nature Communications. Thread below: (1/6) doi.org/10.1038/s41467…

Friends, Romans, Transcriptionmen, this is not to be missed. Free access live and online. October 10th Université de Genève

Pre-announcement of a CNRS tenure-track position 2024 “RNA Modifications” at the Centre for Integrative Biology (CBI), Toulouse, France CNRS 🌍 tenure-track positions/Junior Professor Chairs to recruit outstanding early-career candidates will open soon (March 2024)

Wonderful to have our paper, "Inherited blood cancer predisposition through altered transcription elongation", published (open access) in Cell today! cell.com/cell/fulltext/… 🧵 (1/n)

I am so excited to share the very first preprint from our lab! This is a productive collaboration work with Michael Tellier lab, がんゲノム動態プロジェクト@がん研, and Shilatifard Lab NELF controls Pol II transcription termination and DNA replication. Check it out!👇 biorxiv.org/cgi/content/sh…

Doctoral student position open in our lab University of Helsinki Life Sciences University of Helsinki Medicine and Health, University of Helsinki Are you interested in RNA Pol II Gene Regulation, transcriptional cyclin-dependent kinases, and how these could be targeted in cancer? Apply by April 5th: jobs.helsinki.fi/job/Helsinki-D… Please RT

Thrilled to share our work on the role of mutated TDP1 in the accumulation of transcriptional DSBs Cell Reports. Thanks to Olivier Sordet Favre/Sordet team , Mathéa Geraud, giovanni capranico and all co-authors Nicolas Bery Lara Fernandez Gilles Favre sciencedirect.com/science/articl…