New online! Methods and applications of in vivo CRISPR screening bit.ly/40BAAy0

New preprint from Hemann lab Koch Institute at MIT In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy biorxiv.org/content/10.110… CRISPR screens in #PancreaticCancer model identifies Nrf2 hyperactivity as a sensitizer to CAR-T cell therapy.

Respiratory viral infections awaken metastatic breast cancer cells in lungs | Nature nature.com/articles/s4158…

Fantastic resource paper from Children’s Research Institute at UT Southwestern investigators in Nature Metabolism utilizing melanoma patient tumors & matched serially passaged PDXs: Conservation and divergence of metabolic phenotypes between patient tumours and matched xenografts nature.com/articles/s4225…

A new tragedy for the Endocrine community An outstanding scientist leaves us too soon UTSW Media Relations National Academy of Sciences Endocrine Society

Registration & Abstract Submission OPEN! Join for the 48th All India Cell Biology Conference & Symposium – the flagship annual meet of Indian Society of Cell Bio Don’t miss the chance to present your research! 🔗 home.iitk.ac.in/~sganesh/aicbc… #CellBiology #AICBCS2025 #ScienceConference

Why does RNA undergo glycosylation? Excited to have our new paper out. We in collab w/ Ryan Flynn show N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells. nature.com/articles/s4158… UConn Health UConn Research

A small-molecule heme oxygenase inhibitor disrupts perivascular macrophage–mediated suppression of T cell responses in preclinical models of cancer science.org/doi/10.1126/sc… Meriem Bahri Arnold Lab Science Translational Medicine

Interact-omics is a high-throughput cytometry-based framework for cellular interaction mapping. Haas Lab nature.com/articles/s4159…

I think a good rule of thumb is to spend at least as much time thinking about your data as you did obtaining it. It's common for people to spend a lot less time thinking than doing which gives rise to all kinds of problems.

The brain is the master regulator of food intake and energy balance. A brilliant new Cell review, including the mechanism of GLP-1 drugs, by Christoffer Clemmensen and colleagues, open-access cell.com/cell/fulltext/…

This is literally one of the simplest guides to mastering productivity:

We are looking for a talented Postdoc to join our Lab MD Anderson Cancer Center ! If you're interested in metabolism, tumor microenvironment, and cutting-edge MS proteomics, and have less than 2 years Postdoc experience, look here 👇 jobs.mdanderson.org/search/jobdeta…

CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma dlvr.it/TMRlml

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard

New work from our lab describing a role for mitochondrial glutathione in breast cancer metastasis ⁦Nicole DelGaudio⁩ ⁦Rockefeller University⁩ aacrjournals.org/cancerdiscover…

"Science is not about finding the 'right' answers; it is about asking the 'right' questions." – C.V. Raman. CSIR-IGIB joins the spirit of the nation in celebrating the 79th Independence Day of India. Image courtesy: Shreya Yadav from Arpan Parichha lab using a confocal laser

New paper out! Triplet immune checkpoint immunotherapy can reactivate highly exhausted TIM3+ CD8+ T-cells in melanoma Moffitt Cancer Center Journal for ImmunoTherapy of Cancer jitc.bmj.com/content/13/8/e…

Amazing nature paper by moran amit & the MD Anderson Cancer Center cancer neuroscience team. Cancer is a wound that does not heal but now we learn that injury phenomenon also extends to nerves! Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy nature.com/articles/s4158…

Delighted to share our Cancer Cell paper published today, co-authored by Dr. Alexander Biederstädt Alexander Biederstädt, MD and Dr. Rafet Basar Rafet reporting the first genome-wide CRISPR screen in primary cord blood NK and CAR NK cells. We identify key genetic checkpoints including