A new study in mice describes the activation programs of neonatal innate-like CD8+ #TCells, spotlighting the roles of #TranscriptionFactors Bach2 and AP-1. Learn more: scim.ag/5Z2 Cornell University Cornell Center for Immunology

The newest story from the Rudd lab is out! Read about how CD8+ T cells are more than just their T cell receptor! Congrats to Ravi K. Patel et al science.org/doi/10.1126/sc…

Read about another fantastic collaboration of Rudd-Grimson lab on innate-like CD8+ T-cells in mice and humans.

How do neonates survive with primitive adaptive immune system? Read about the functionally diverse pool of CD8+ T-cells that may compensate for the primitive adaptive immune system of neonates. scim.ag/5Z2 Science Immunology #SingleCell #multiomics #neonatalImmunity

'Keep the child within us alive'. Highly reactive, innate-like T cells of childhood are also found in adulthood in both mice and humans, changing how we think about the T-cell biology in adults scim.ag/5Z2 Science Immunology #SingleCell #multiomics #neonatalImmunity

Science Immunology This paper is beautiful ➡️ science.org/doi/10.1126/sc… To be paired with this vintage 💎 science.org/doi/10.1126/sc…

A new Science Immunology study describes why a subset of T cells behaves in a way that is more similar to innate immune cells, rather than responding like normal adaptive immune cells. Learn more: scim.ag/603

New research in mice finds that neonatal CD8+ T cells can undergo rapid chromatin remodeling, which supports their innate-like functions. Read more: scim.ag/607 Cornell University Cornell Center for Immunology

Not at all jumping on the AI rodent band wagon, but delighted to announce the publication of our paper in Mucosal Immunology about why you lose your appetite when you have a cold pubmed.ncbi.nlm.nih.gov/38382577/ Including the coolest experiment I have ever done

Excited to share our manuscript on single-cell and spatial multi-omics of anti-integrin therapy in ulcerative colitis (UC) nature.com/articles/s4146…. This work was led by Elvira Mennillo, in collaboration with Alexis Combes, @GabiFragiadaks, and Angela Oliveira Pisco 1/8

I am excited to share that our #IMPACC paper - Integrated longitudinal multi-omics study identifies immune programs associated with acute COVID-19 severity and mortality - was recently published in Journal of Clinical Investigation. jci.org/articles/view/… #SystemsBiology #Bioinformatics [1/5]

Steroids have *compartment-specific* effects in patients with COVID-19 ARDS! Results highlight importance of studying injured organs directly when possible Nature Communications with Lucile Neyton, Ravi K. Patel, Gabi Fragiadakis and colleagues nature.com/articles/s4146…