This is worth a few minutes to learn more about the inspiring work from Peter Aldhous Eugenie Reich Elisabeth Bik

The troubling state of play in Alzheimer’s research – my The New York Times op-ed today. nytimes.com/2024/07/07/opi…

Despite U.S. FDA approvals of 2 drugs for Alzheimer's disease, the evidence for their benefit vs harm is soft and the β-amyloid hypothesis is still unproven nytimes.com/2024/07/07/opi… by Charles Piller New York Times Opinion

The countdown has begun!! Amazing work again by Aarhus Uni.hospital Claus Z. Simonsen and the ophthalmologists. Aarhus has now recruited their 11th patient and our study has just 10 to go. 68/78 So exciting! Petra Ijäs Dr. Peter Vanacker Louisa M Christensen Lauren Sanders Andrej Khanevski Michael Mazya

News out of Cassava $SAVA this morning. Hopefully new leaders will see their ethical responsibility to stop this clinical trial. cassavasciences.com/news-releases/…

Today, let's do a mini #ImageForensics tutorial using imagetwin, making use of its large database of (Open Access) published images. This database allows the software to find duplicates between scientific papers. I will just live-tweet what I find. /

🚨REVISION Trial! 👁️Does Early REperfusion therapy with intravenous alteplase help recovery of VISION in acute central retinal artery occlusion? ⭕️Adaptive design with interim analysis ⭕️Up to 422 participants to be recruited journals.sagepub.com/doi/full/10.11… Sven Poli

Lecanemab denied approval by European Union’s drug regulator, citing risks outweighing very small benefits. reuters.com/business/healt…

What a milestone! Our 70th patient was recruited Oslounivsykehus ! Fantastisk teamwork once again by prehospital services, Ahus , Dept. Of ophthalmology Ullevål & the on-call neuro team at Rikshospitalet. 8 to go🥳 Anne Hege Aamodt Claus Z. Simonsen Petra Ijäs Lauren Sanders

I think it's time to abandon rather than expand the prion paradigm, which is still as weak, mechanistically baseless & therapeutically sterile as the day it was postulated, leading a whole field astray for four decades. By failing to understand the..1/10 jamanetwork.com/journals/jaman…

Beware of the ‘prionization’ of #Alzheimers & #Parkinsons. Stanley Prusiner, the 1997 Nobel Prize winner, co-authored the most-viewed JAMA Neurology paper last week, suggesting these are prion diseases (1/7) jamanetwork.com/journals/jaman…

Dear neurology colleagues, please be on the lookout for this stroke mechanism. ahajournals.org/doi/abs/10.116…

Elsevier decided to retraced some(all??) of the chapters by Hari Shanker Sharma, lagging Springer by about 6 months. Everything I reported is on Pubpeer pubpeer.com/search?q=hari+… Dead Neanderthals Cheshire have been investigating authorship funnies in this case.

I refuse to be forced to use synuclein seed assays in clinical trials in Parkinson’s disease without more debate. Neuronal synuclein disease is a clinically irrelevant term that needs swatting before it spreads The biological approach to Alzheimer’s has led to chaos

Patients with hereditary hemorrhagic telangiectasia (HHT) received pomalidomide or placebo for 24 weeks. Pomalidomide reduced epistaxis frequency and severity. Full PATH-HHT trial results: nej.md/3MUk9VW

Months later, imprints of graffiti, including phrases like “death 2 israhell” and “kill cops,” remain visible on the historic sandstone features of Stanford University’s Main Quad. The new schoolyear begins next week but scars of last year have clearly and literally yet to heal.

Outstanding picture, Rebecca Embalabala!