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Exciting insights from our BSCMR Valve Consortium, presented at #CMR2024 and featured in #EHJ: In severe AS, myocardial scar detected by #whyCMR pre-operatively is linked to long-term survival post-AVR. This underscores theimportance of fibrosis for post-op risk stratification.

Here we go again! Want to see if the coronary sinus reducer works in refractory angina? Watch Michael Foley present the results of the ORBITA-COSMIC in the main arena at #ACC this Monday #ORBITA Fiyyaz Ahmed-Jushuf Matthew Shun-Shin Shayna Chotai Christopher Rajkumar Florentina Simader

Amazing to see a brilliant friend and colleague Michael Foley present the #ORBITA-COSMIC trial of the coronary sinus reducer with simultaneous publication in The Lancet Rasha Al-Lamee NHLI Imperial NHS 💙 #ACC2024 thelancet.com/journals/lance…

Q: Does blinding matter in RCTs of surgical procedures? A: Depends on the endpoint JAMA Surgery We compared placebo-controlled and open-label surgical trials to identify when the placebo effect is most powerful Rasha Al-Lamee Katie Thomas NHLI jamanetwork.com/journals/jamas…

In ORBITA-STAR, angina verification with an ischaemic stimulus powerfully predicted response to PCI. #EuroPCR2024 Perhaps we have been too focused on treatment when the problem always lay in the diagnosis! Published today in #JACC jacc.org/doi/10.1016/j.… Rasha Al-Lamee

Always a privilege to work with incredible statisticians (and cardiologists) Frank Harrell and Matthew Shun-Shin. This time for ORBITA-STAR. NHLI Imperial NHS 💙 JACC Journals

ORBITA-STAR at #EuroPCR is a fascinating & successful study of type of chest pain as a predictor of PCI success. Very difficult to ascertain if angina caused by ischemia is what patients felt. This was a concern of Gruentzig's 40 yrs ago! Christopher Rajkumar Rasha Al-Lamee #AngioHistory

Thanks to JACC Journals and PCRonline 🫀 for showcasing, and the patients who made ORBITA-STAR possible! Hopefully a step toward more targeted treatment.

Excellent discussion of ORBITA-STAR by Michael Chen Simple findings like those made in this study pave the way to solve a major clinical problem. In stable patients, persistent angina is PCI’s Achilles’ heel TCTMD PCRonline 🫀 Rasha Al-Lamee

Check out our journal club with OPCI on ORBITA-STAR and the symptom stratified analysis of ORBITA-2 Rasha Al-Lamee Florentina Simader NHLI

Should PCI be an option for first line management of stable angina symptoms? Point and counterpoint in Circ: CQO with final word from Brahmajee Nallamothu and TCTMD ahajournals.org/doi/full/10.11… Rasha Al-Lamee

I think so, what else explains an initial high event rate which then subsides (aortic stenosis doesn’t get better!)? Great if you can manage the first 6 months of subtraction anxiety - event rate then tracks the TAVR arm. Psychology so important in clinical trials. John Mandrola, MD

Join us at our Cardiology Review Course with Mayo Clinic from Monday 10 - Friday 14 March at Royal College of Physicians >> tinyurl.com/BCSMayoCRC. This five-day course is in its 17th year and provides a comprehensive opportunity to update your knowledge through lectures and interactive

Are the Appropriate Use Criteria (AUC) for revascularization still aligned with the latest evidence? New insights from ISCHEMIA challenge key assumptions. My two cents in Circ: CQO It’s time to rethink outdated priorities. tinyurl.com/cupe7hx8

Great morning at Royal College of Physicians talking about preventive Cardiology on the British Cardiovascular Society Mayo Clinic CV Cardiology Review Course Lots of old friends and great questions! Rajiv Gulati Christopher Rajkumar Shouvik Haldar Sudhir Rathore, Louise Buchanan and Malcolm Bell #crc2025

Tons of high-value case-based presentations covering CAD arrhythmia HF shock and more. Come join! Benjamin Hibbert Stanislav Henkin Abdallah El Sabbagh Phillip Rowse, MD, FACS Christopher DeSimone, MD, PhD Claire Raphael Christopher Rajkumar Mayo Clinic Rochester Cardiology Fellows

𝐃𝐒𝐄 𝐝𝐞𝐥𝐢𝐯𝐞𝐫𝐬 𝐢𝐧 𝐎𝐑𝐁𝐈𝐓𝐀-𝟐: Stress echo ischemia identifies who 𝘳𝘦𝘢𝘭𝘭𝘺 benefits from PCI. 📖 𝐉𝐮𝐬𝐭 𝐩𝐮𝐛𝐥𝐢𝐬𝐡𝐞𝐝 𝐢𝐧 #𝐉𝐀𝐂𝐂: bit.ly/42PNCcB Rasha Al-Lamee Matthew Shun-Shin Christopher Rajkumar Michael Foley Florentina Simader Shayna Chotai

#EuroPCR 2025 PCR’s Got TALENT 1️⃣ 3 min / 3 slides 2️⃣ 5 min / 5 slides 3️⃣ 8 min / 8 slides 🫵 Support & VOTE ! Previous WINNERS include superstars 🌟Dr Ziad Ali 🌟Dr Dejan Milasinovic 🌟Dr Tom Ford 🌟Dr Christopher Rajkumar 📌 Starts today 12:00, Rm 252A

Had a great time at #ECAS2025 as the only interventionalist at an EP conference! Fantastic to see a full session on the placebo effect in cardiology. Thanks to the organizers for the invite ECAS - HeartRhythm . Now to #EuroPCR PCRonline 🫀