
PALACE Trial
@palace_trial
The PALACE is an international, multicenter randomized control trial using the PEN-FAST tool to risk-stratify penicillin allergy labels in adult outpatients.
ID: 1532447986999087105
02-06-2022 19:44:43
68 Tweet
244 Followers
420 Following

Wow! 🔥The PALACE RCT 🔥 Jason Trubiano 🆔 et Al JAMA Internal Medicine Direct oral penicillin challenge in patients with a low-risk penicillin allergy was noninferior compared with standard-of-care skin testing followed by oral challenge Thanks Ignacio uman jamanetwork.com/journals/jamai…



After an amazing 24 hrs and a lot of #IDtwitter 🩷 I thought I would provide my thoughts on our PALACE Trial in JAMA Internal Medicine and how we got here! Direct oral challenge (DOC) vs. skin testing + oral challenge (SOC) for low-risk #penicillinallergy jamanetwork.com/journals/jamai… 1/4

If a patient had a mild reaction to penicillin/amoxicillin longer than 5 years ago or any mild reaction that did not require treatment, clinicians can skip the allergy evaluation and perform the challenge themselves.Jason Trubiano 🆔 Centre for Antibiotic Allergy & Research Allergy Immunology MUHC @vumc_cdsi_rsch Duke Antimicrobial Stewardship

Thanks NEJM Journal Watch for the review of the PALACE Trial in JAMA Internal Medicine - #PENFAST #penicillinallergy #DOC Infectious Diseases at Austin Health Doherty Institute UniMelb MDHS

Super proud of the team led by Kyra Chua @Jamie_L_Waldron Centre for Antibiotic Allergy & Research Infectious Diseases at Austin Health for this pilot work bringing #penicillinallergy #oralchallenge #DOC to #generalpractice RACGP. 👏 ➡️ jaci-inpractice.org/article/S2213-…

“Penicillin Allergy Evaluation Should Be Performed Proactively in Patients with a Penicillin Allergy Label – A Position Statement of AAAAI Cc Ana Copaescu Jason Trubiano 🆔 Eric Macy Kimberly Blumenthal, MD, MSc #PALACE #IDXposts aaaai.org/Aaaai/media/Me…

What’s Hot This Year in ID Clinical Science | Clinical Infectious Diseases | Great to 👀 the PALACE Trial in the list ❤️ Thanks to authors & Clinical Infectious Diseases 👏 #penicillinallergy #PENFAST in ID practice ✅ academic.oup.com/cid/advance-ar…




Joe De Luca PREPARE RCT results! Perioperative #penicillinallergy assessment via digital assessment safe! Your heard the results here 1st at #AAAAI24 🙌 Centre for Antibiotic Allergy & Research Infectious Diseases at Austin Health UniMelb MDHS


Ana Copaescu #AAAAI24 PALACE Trial Follow up results…. 93% believe not allergic at 6m with 38% tolerating a treatment course. Infectious Diseases at Austin Health Centre for Antibiotic Allergy & Research Doherty Institute


The PALACE Trial: Rethinking How to Assess, Document, and Code New Penicillin Allergies: « This is a call to action for primary care. » Kevin Fernando medscape.com/viewarticle/10…

So exciting 🎉 - Inpatient 🌎 #penicillinallergy #delabeling data from 30 sites and 4 countries to date that will inform #drugallergy and #AMS practice from 🇦🇺, 🇬🇧, 🇿🇦, 🇲🇾 and more to come shortly… (spoiler alert 🦫, 🗽, 🥝….). Reach out to join us Centre for Antibiotic Allergy & Research Elise Mitri 🫵


The PALACE Trial study has demonstrated that single-dose DOC in low-risk patients reporting a penicillin allergy is safe and effective at immediate (5 days) and prolonged follow-up (6 months). ja.ma/4fLY4pN Ana Copaescu Allergy Immunology MUHC Jason Trubiano 🆔 Centre for Antibiotic Allergy & Research

Don't miss out on #DHS2024 Doherty Institute !! 🚨Breaking news Centre for Antibiotic Allergy & Research 🚨 ➡️> 10 New #drugallergy Data Abstracts ➡️ New data on the latest member of the #PENFAST "family" ➡️Launch of a National Antibiotic Allergy Network Inpatient Penicillin Allergy Guide in #AMS ➡️Launch of new Antibiotic Allergy