🚨 Exciting news! The 3rd Annual Quantitative Biodesign Symposium will be held here at Duke University’s on Oct 14-15, 2024. This year’s theme: “AI in Biodesign” 🤖🧬. Registration is FREE! Last day to register: Oct 7, 2024. More info: lnkd.in/ebWkRnvi #AI #Biodesign

Really excited to finally share this work from my internship at Microsoft Research in summer 2023! This project began when Judith and Kevin raised a simple question: can we develop better latent mappings of olfactory stimuli, such as molecules to odor perception? Summary (1/12):

A certain recorded talk may have finally dropped on Machine learning for protein engineering seminar YT! ESM3: youtu.be/qeqbm8a1-ZA Stay tuned for more talks to upload throughout this week❤️

Today, we’re proud to announce the launch of Ginkgo Datapoints to usher in the next era of biotechnology by making the training of AI models easier and more efficient. hubs.la/Q02QfjFj0

The MIT Bioinformatics Seminar is back this semester! We have an exciting series of speakers, with some joining virtually and others hybrid/in-person. Please check out the talk schedule here: math.mit.edu/compbiosem/. (1/n)

1. Accurately predicting enzyme functions through geometric graph learning on ESMFold-predicted structures nature.com/articles/s4146… 2. Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists biorxiv.org/content/10.110… 3. Manufacturing-Aware Generative

Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures | Nature Methods - Genomics 2 Proteins (G2P) portal, linking 20,076,998 genetic variants to 42,413 protein sequences and 77,923 structures (58,027

Protein interactions in human pathogens revealed through deep learning Nature Microbiology Institute for Protein Design 🚀 New paper from David Baker! 🚀 1. Revolutionary Method for PPI Prediction: The study introduces RoseTTAFold2-Lite, a novel deep learning model for identifying and

How can we build an Al Virtual Cell 🔮🧬 that simulates all functions and interactions of a cell? How will it transform research and drive breakthroughs in programmable biology, drug discovery and personalized medicine? 🚀 Take a look at our Perspective! arxiv.org/pdf/2409.11654

Congratulations to this year’s #LaskerAward winners! Basic: Zhijian “James” Chen Clinical: Joel Habener, Lotte Bjerre Knudsen, Svetlana Mojsov Public Service: Quarraisha Abdool Karim and Salim Abdool Karim laskerfoundation.org/winners/2024-w… #Lasker2024 #LaskerLaureate #UTSWMed #NovoNordisk

How can AI bring us closer to the vision of a virtual cell that predicts cell behavior? Excited to share our perspective on what a virtual cell should do, how it can be built with AI and how it could impact biological discovery w/ Charlotte Bunne, Yanay Rosen arxiv.org/abs/2409.11654

How to Build the Virtual Cell with Artificial Intelligence: Priorities and Opportunities "Here we propose a vision of AI-powered Virtual Cells, where robust representations of cells and cellular systems under different conditions are directly learned from growing biological data

Congratulations to biochemist Zhijian “James” Chen, Ph.D., who has been awarded the 2024 Albert Lasker Basic Medical Research Award for his discovery of the cGAS enzyme. Read more: bit.ly/4e9ITFU. UT Southwestern Medical Center Lasker Foundation

1. Design of Ligand-Binding Proteins with Atomic Flow Matching arxiv.org/abs/2409.12080 2. Manifold-Constrained Nucleus-Level Denoising Diffusion Model for Structure-Based Drug Design arxiv.org/abs/2409.10584 3. Opponent Shaping for Antibody Development arxiv.org/abs/2409.10588 4.

Zero-shot transfer of protein sequence likelihood models to thermostability prediction | Nature Machine Intelligence - Evaluate various protein models (ProteinMPNN, MIF, MIF-ST, ESM-IF, ESM-1V, ESM-2, MSA Transformer, Tranception, Ankh) over stability datasets (Q3421, K2369, Ssym, S461) in a

Let me tell you a story. It'll end up at the current tech-bio and protein design scene. But the story starts about 25 years earlier. Did you know that, commercially, the human genome project precipitated the end and not the start of a genomics boom? 1/

1 million paired TCR sequences for < $200. Congrats Paul G Thomas and team biorxiv.org/content/10.110…

A beautiful thread from Rohit Singh!! 🧵 It really captures my feelings/frustration about current "trends" in protein design. As Rohit mentioned, the aftermath of sequencing the human genome has been a huge huge disappointment. Genomics has really not lived up to the hype,

AlphaFold2 and AlphaFold3 leads to significantly different results in human-parasite interaction prediction biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

🌟 2024 Biomarkers of Aging Conference Speaker Highlight 🌟 We’re excited to welcome Jonathan Gootemberg (Jonathan Gootenberg) and Omar Abudayyeh (Omar Abudayyeh) to Day 1 of the 2024 Biomarkers of Aging Conference! Jonathan Gootenberg, Ph.D. is an Assistant Professor at Harvard Medical