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New paper in Imaging Neuroscience by Kenneth Shinozuka, Morten L. Kringelbach, et al: LSD flattens the hierarchy of directed information flow in fast whole-brain dynamics direct.mit.edu/imag/article/d…

These findings are from a study in Nature Aging which applied dimensionality reduction to clinical data to generate a clinical aging clock (PCAge) identifying signatures (principal components) separating healthy and unhealthy aging trajectories. nature.com/articles/s4358… 2/10

🫶 this review out in TICS cell.com/trends/cogniti… on problems with biomarkers in psychiatry @AvramHolmes Alex Fornito Linden Parkes + dovetails well with some of our ideas : nature.com/articles/s4139… w/ Martijn Figee & David Roalf.

New Biomarker Links Brain Waste Clearance to Vascular Dementia A study has identified a biomarker called DTI-ALPS that links glymphatic system dysfunction to cognitive decline in vascular dementia. By analyzing MRI scans and cognitive tests from over 3,750 participants,

That seems to be enough to buy gains in longevity and brain and heart health. At least 150min/week is doable.

Deep Sleep Drives Brain’s Waste Clearance, Aiding Cognitive Health Deep sleep is vital for brain health, as it clears waste through the glymphatic system, which relies on norepinephrine-driven pulsations in blood vessels. These waves occur about every 50 seconds during deep

Sleep Loss Weakens Brain’s Ability to Block Unwanted Memories Sleep deprivation impairs the brain's ability to suppress unwanted memories, a function critical for maintaining mental health. In a study, well-rested participants could engage the prefrontal cortex to block

Challenge to do scalp (F3 here) vs. fMRI-guided rTMS outcome because, by chance, scalp sometimes = decent fMRI spot. This study in ASD shows nicely: scalp with high FC does better + fMRI target works++; amygdala FC treating kids as young as 2 yrs old biologicalpsychiatryjournal.com/article/S0006-…

Late-onset epilepsy and neurodegeneration: intersecting mechanisms or separate entities? New scientific commentary by Xin You Tai and Marian Galovic tinyurl.com/563dwhbr

Long COVID Impairs Exercise Capacity and Cognition for Years A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) found that two-thirds still experienced persistent symptoms like reduced exercise capacity and impaired cognitive performance two years after their

Well-deserved! Definitely worth attending.

What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵 jamanetwork.com/journals/jamap…

Covert consciousness, where unresponsive patients willfully modulate brain activity to command, is gaining attention. But these assessments are fundamentally limited. What if we could just... read their minds instead? 🧵 about our paper in Neurology Journal neurology.org/doi/10.1212/WN…

Facial expression changes track depression severity better than standard assessments. nature study showed that in severely depressed patients treated with DBS, facial dynamic or brain activity can forecast relapse or remission by up to 5 weeks in advance, compared to

Dr Emily Dennis created ENIGMA-U, an incredible FREE online neuroscience, neuroimaging, + neuropsych course geared toward adv HS/entry-level univ. students - link in the comments below [1] 💡40 videos + a total of 12.5 hrs of material now live on YouTube! 💡Unbelievable content:

A wearable, battery-powered rTMS device has been engineered. Weighing under 7lbs and consumes 90% less energy than typical TMS systems, this device enables brain stimulation to be done anywhere.

Prediction of mental health risk in adolescents nature.com/articles/s4159…

Outcomes for the first 60 MDD patients treated at our clinic Queensland Neurostimulation Centre with robotically delivered & fMRI-personalized rTMS MADRS response=74%, remission=53% for RCT patients EXCITED to see fMRI moving from research to real-world clinical use! karger.com/pps/article/do…

April is National Occupational Therapy Month! Join us in celebrating the incredible occupational therapists who help individuals rebuild skills, regain independence, and thrive after brain injury. Thank you for all you do! #OTMonth #NeuroResilience

Renewed focus on modifiable factors across the lifespan for improved #brainhealth in athletes (& the rest of us)! Benjamin Brett Concussion in Sport Group American Academy of Neurology UCLA Steve Tisch BrainSPORT Program UCLA Neurosurgery 🧠 UCLA Pediatric Neurology Kevin Bickart Bill Flavin Sports Neuro Society American Neurological Association FLICNA