The latest version of Activity Metabolomics and Mass Spectrometry (AMMS 2025) is now in the proof stage. AMMS 2025 has two new chapters, lipids, and a lot of polishing. Still free as PDF, and royalty-free on Amazon. Coming as soon as we get the proofs (and are happy with them).

AMMS 2025 book is live, the PDF just came available, and you can freely download the entire book here... masspec.scripps.edu/about/mass-spe… Two new chapters, new sections, and refinements throughout. The royalty-free print version of #AMMS 2025 will be available on Amazon next week.

“Because they wouldn’t let me give it away” my answer when people ask why did I not publish AMMS with a publishing house. Free PDF at Scripps Research: masspec.scripps.edu/about/mass-spe… Royalty-free print version at Amazon ($15.08): a.co/d/8dEWO8a

“Therefore, the "dark matter" of metabolomics is largely explainable.” in a new paper by Shuzhao Li. biorxiv.org/content/10.110… nature.com/articles/s4225…

I guess people just like free stuff. The pdf of AMMS 2025 just went over 2000 downloads. masspec.scripps.edu/about/mass-spe… Very glad to see it getting used. And I appreciate the feedback! The next version I've been developing will have some especially interesting features.

Krakatoa doesn't have to just mean violent destruction. Close to real-time proteeomics was achieved via a combined effort between Cedars-Sinai and Cinder with their unique hypothermophile enzyme "Krakatoa" pubs.acs.org/doi/10.1021/ac…

Unexpected growth on the #METLIN front, now reaching 960K molecular standards with MS/MS natural product additions. 960K METLIN currently available online via XCMS-METLIN. xcmsonline.scripps.edu @Molsystbio doi.org/10.1038/s44320…

Recent Beamish award winner Tao Huan Nature Metabolism University of British Columbia describes how to avoid “nonsensical” results in metabolomics doi.org/10.1038/s42255…

At least a partial explanation for all the unidentifiable peaks we see in LC/MS/MS experiments of small molecules. More details on the experiments and how ISF determinations were made at doi.org/10.1002/ansa.7… and doi.org/10.1038/s42255…

An AI BioSync rendition of METLIN 960K as a dot matrix. Celebrating the creation of METLIN with 960,000 molecular standards, and going live in its original classic form - reengineered. 🔗 Sign in for access: metlin.scripps.edu/auth-login.html 📖 Read more: DOI: 10.1002/ansa.70012

New metabolic reactions uncovered by isotope labeling. Excellent work by Jiang Zhu doi.org/10.1038/s41467…

Lipidomics (& #METLIN) reveal a metabolic vulnerability in tumors nature doi.org/10.1038/s41586… Tumors don’t just synthesize their own lipids—they scavenge antioxidant-rich lipoproteins. Javier Garcia-Bermudez w/ our lab's lipidomics uncover how this can be used to impair tumor growth

A free version just posted—courtesy of nature and Javier Garcia-Bermudez on cancer lipidomics. rdcu.be/eqx3e Lipidomics (via #XCMS/#METLIN) reveals α-tocopherol (vitamin E) as a key player in mediating cancer cell death. #Lipidomics #CancerResearch #Ferroptosis #VitaminE

Lipidomics combined with CRISPR can help decipher the complex biochemistry that allow cancer cells to evade elimination. doi.org/10.1038/s41586… nature fruitful collaboration with Javier Garcia-Bermudez #VitaminE

Outstanding keynote by Dr. Erin Baker. Wonderful to have #exposomics prominently covered at #MetSoc2025

Additional thoughts on this #Lipidomics #CRISPR topic… we still need to decipher the roles of some of the lipids we observed. Lipids we find equally as intriguing as the original tocopherol (vitamin E) lipid.

Cancer's secret weapon. Nice to see the implications of Javier Garcia-Bermudez revelation - #HDL and #VitaminE continue to gain interest nature #CRISPR #Lipidomics nature.com/articles/s4158… yahoo.com/news/us-resear…

With Katerina Rohlenova pleased to announce the 2026 Prague Metabolism and Signaling Meeting (June 24-27). Two Keynotes (Vousden & Hall) and 30+ speakers in metabolism, mitochondria, aging, mTOR, & more. Please RT. Info, registration, & student discounts at: praguemetabolismsymposium.com

On the front cover of month's issue: "Evaluating Ion Mobility Data Acquisition, Calibration, and Processing for Small Molecules: A Cross-Platform Assessment of Drift Tube and Traveling Wave Methodologies" Read it here 🔗brnw.ch/21wTYQ3 #JASMS