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There's a buzz around Multi-pass, Single-Molecule Nanopore Reading of Long Protein Strands, a recent nature publication from Jeff Nivala, Keisuke Motone / 元根 啓佑, Daphne Kontogiorgos-Heintz and colleagues. Watch this publication highlight where they discuss their work! youtube.com/watch?v=aaE7kZ…

The AksimentievLab and @leunglab reveal 3D structures of poly(ADP-ribose) using SAXS and MD simulations, demonstrating how cation concentration and polymer length influence PAR's structure, providing insights into functional roles of a homopolymer nature.com/articles/s4146…

Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair for somatic benchmarks biorxiv.org/cgi/content/sh… #biorxiv_genomic

DYK TDCC @genometdcc.bsky.social collaborates with Genome Technology Developers, Innovators, and Expert Users? Our YouTube showcases their work sequencing, synthbio, and genomic tech. Check out the latest 📽️👇 youtube.com/@genometdcc Supported by National Human Genome Research Institute in collaboration w/ The Jackson Laboratory

What’s the connection of Dr. Stan Fields to @FPRoth fascination w/multiplexed assays of variant effects? Learn the answer on the VUS podcast led by Alex N Nguyen Ba . UW Genome Sciences University of Pittsburgh open.spotify.com/episode/2rebpK…

Nanopore-Based Protein Analysis Approaches Feasibility. Academic and industry-affiliated research groups are tackling the technical hurdles and placing nanopore-based protein analyzers in the hands of early adopters. genomeweb.com/proteomics-pro…

Join our upcoming #RNAmodifications webinar on Oct 23rd! Learn from experts about new technologies, the challenges of detecting RNA modifications, and the role of reverse transcriptase enzymes. Register is open! bit.ly/3TULhbr #RNA #RNAResearch #RNAstructure

Available now via bioRxiv is our preprint on live-cell transcriptomics with engineered virus-like particles Broad Institute biorxiv.org/content/10.110…

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

Very happy to share our latest work ACS Nano on applying #nanopore to protein analysis! With the motor protein Hel308, we translocate DNA-peptide conjugate through MspA and successfully distinguish sulfation and phosphorylation at #singlemolecule level.

Our paper on continuous mutagenesis in living cells using HACE is now out in Science Magazine! We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks. science.org/doi/10.1126/sc…

Glad to share our latest review article on #ChromatinTracing, published with Springer Nature in Nature Reviews Methods Primers Nature Reviews Methods Primers! TDCC @genometdcc.bsky.social 4DNucleome SenNet Consortium NIH Common Fund Yale School of Medicine @3D_Genome The 3D Genome Gene Regulation nature.com/articles/s4358…

Kicking off the annual CEGS meeting in La Jolla, CA! Hosted by the Center for Admixture Science and Technology. Learn more about the ongoing work by all the Centers of Excellence in Genomic Science at genome.gov/Funded-Program…

Center for Genome Editing and Recording 🧬📼 5-day CRISPR training workshop for college-level instructors from HBCUs. Learn hands-on genome editing techniques to start new genome editing courses or incorporate into existing classes. Apply by Nov 30 👇 app.smartsheet.com/b/form/7354618…

Center of Excellence in Genomic Science Annual Meeting at Scripps Seaside Forum 🌅 Learn more about these CEGS Centers, their research, and outreach programs by visiting genome.gov/Funded-Program…

We’re excited to announce our first speaker of London Calling 2025 Jeff Nivala will share their groundbreaking ‘proof-of-concept' method showcasing the capability of #nanopore sequencing to read #polypeptide strands – a major step forward in protein analysis.

Every day we're shuffling...genomes 🕺🧬 In this video Sudarshan Pinglay describes how Genome-Shuffle-seq enables multiplex generation, mapping, and characterization of structural variants. Paper recently published in Science Magazine 👇 youtu.be/rW8AFhq1Pys

Fresh off the press in Nature Methods In this highlight video, Siyuan (Steven) Wang and Yubao Cheng at Yale University unveil a powerful new platform to decode 3D genome architecture. Perturb-tracing IDs new regulators of chromatin organization at multiple length scales. youtu.be/oR63uI8feWs

Postdoc Position Available Interested in #Nanopore Direct Sequencing of #RNA? Ya-Ming Hou at Thomas Jefferson University is seeking candidates with #bioinformatics skills Send cover letter, CV, and references For contact information, visit houlaboratory.com/contact