Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells go.nature.com/3XeDg1Q

Out today from the Vandenberg and Dedecker labs! PSF splitting with the ‘Circulator’, which encodes the fluorophore emission band into the PSF, improves the information content of fluorescence microscopy and enables improved super-resolution imaging and single-particle tracking.

A video of the Danish percussion duo Safri Duo performing the "Interstellar" theme

Published today in nature, we describe an approach for single-molecule protein reading on Oxford Nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity. nature.com/articles/s4158…

International Chess Federation Congratulations to Team India 🇮🇳♥️ They have played exceptional will throughout the Chess Olympiad 2024 ✨

Tremendously proud to share my fellowship work, online today in Nature Medicine. We tried to understand why CAR T therapy for AML doesn't work as well as we hoped it would, and how we can solve that. 👇🧵1/10 Penn Medicine CHOP Research Saar Gill nature.com/articles/s4159…

Why do AML patients with African ancestry have poor outcomes? Fascinating results indicate that genetics alter AML biology. Also, its Bailee Kain's first co-first author postdoc pub. Bailee Kain AK Eisfeld Nathan Salomonis and Elaine Mardis nature.com/articles/s4158…

UNREAL!!! Unedited iPhone shots from Watertown, South Dakota!! Easily the deepest reds I’ve ever seen in the aurora! Still going!! #aurora

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

The heart in a zebrafish embryo videoed through a microscope. 72 hour post fertilization (hpf). #CellBiology

In a phase 1 trial, patients with AML treated with CD123 CAR T therapy experienced high levels of cytokine release syndrome and short lived clinical responses, likely due to CAR T-derived cytokines increasing viability of blasts. nature.com/articles/s4159…

New paper from our group in nature by Yiyun Lin @junkewang Kaile Wang and team reporting the unexpected discovery of aneuploid epithelial cells (3%) in normal breast tissues from healthy women raising the question of when is cancer really cancer? nature.com/articles/s4158…

A single molecule provides a controllable connection between a normal metal and a superconductor Letter: go.aps.org/4cAmz8w Focus: go.aps.org/3G0ETLL

📢 New KFW Lab paper out now in Science Advances! 📢 We show that AML cells resist chemotherapy by reversing the ATP synthase reaction—supporting oxidative metabolism and maintaining mitochondrial membrane potential. 🔬🧬 👉 science.org/doi/10.1126/sc…

T cell-derived interleukin-9 potentiates differentiation of GC memory precursors into functional memory B cells in a manner dependent on the transcriptional regulator ZBTB18 Immunity cell.com/immunity/fullt… on cell.com/immunity/fullt…

Yup

3+ days and still waiting.. is this still a domestic overnight ‘express’? Don’t let your agents make promises you can’t deliver on DTDC Express Limited

Delighted to share our latest work deciphering the landscape of chromatin accessibility and modeling the DNA sequence syntax rules underlying gene regulation during human development! biorxiv.org/content/10.110…. Read on for more 🧵 [1/16]

Thrilled to share our work on the role of taurine in myeloid leukemia progression in @nature today! nature.com/articles/s4158…