Proud to share our latest work showing that interactions between strains govern the eco-evo dynamics of microbial communities, led by Akshit Goyal Akshit Goyal, Leonora Bittleston Leonora Bittleston and Gabriel Leventhal Gabriel Leventhal ... biorxiv.org/content/10.110…

Really excited to see our work out mapping the development of the human intestine at single cell resolution. An amazing amount of work from a fantastic team. cell.com/cell/fulltext/…

Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 drive.google.com/file/d/1oH4W0z…

The Smillie Lab opens March at MassGeneral Medicine! We develop methods (wet/dry) to understand microbial life on the human body #microbiome #singlecell #evolution #deeplearning. Hiring grad students, postdocs, and RAs Harvard Medical School Broad Institute. Please share! smillielab.org

Happy that our single-cell meta-analysis of SARS-CoV-2 entry genes is out Nature Medicine. Headed by Chris Muus & Malte Luecken in a big effort of the whole Human Cell Atlas Lung Network, we find age&sex-dependent cell-type specific effects across 31 studies. nature.com/articles/s4159…

I am incredibly excited to share our preprint ‘Somatic mutation rates scale with lifespan across mammals’In this paper we provide an unprecedented description of somatic mutation across mammals. biorxiv.org/content/10.110… An illustrated tweetorial…[1/17]

We are excited to share our study on spatially organized multicellular immune hubs in human colorectal cancer cell.com/cell/fulltext/… Cell. Joint effort with @karin_pelka, Jonathan Chen, Ana Anderson lab, Orit Rozenblatt-Rosen, Aviv Regev, Nir Hacohen, many others!

The Smillie Lab is hiring for an exciting collaboration Broad Institute to identify microbiome products that control gut disease. We are a new computational lab Harvard Medical School @mghmedicine studying #microbiome #immunology #metabolomics #ML. Please share! smillielab.org

Congratulations to Fatima Hussain @fatiays and Javier Dubert on their new paper in Science describing surprising ways how bacteria in the wild defend themselves against phage. See also perspective by Perspective by Meaden and Fineran. science.org/doi/10.1126/sc…

Great lab Harvard T.H. Chan School of Public Health for genomics, lung biology, and asthma!

Very excited to share our work that defines how dopamine and acetylcholine interact in the brain during decision making! biorxiv.org/content/10.110…

Congrats Itzhak Khait, Ohad Lewin-Epstein, and Hadany Lab for their brilliant use of #ML to study plant communication by sound! Ohad is a new postdoc in our lab who is studying how the #microbiome controls its human host - excited to see what he comes up with next! cell.com/cell/fulltext/…

PhD opportunities to join our lab! IMPRS is a great graduate school. Check it out! Deadline for applications: May 15th - contact us if interested 😉