Suicidology Predicting Suicide Death A recent study looking at >2M Americans presenting to ERs with MH concern shows the difficulty of "predicting suicide" - we can't predict suicide to help guide important clinical decisions. The problem: Sensitivity vs PPV /1

👋🏻 Psychiatrist w/ additional training in lifestyle interventions for mental health here This comment is just wrong. Exercise can be a great tool. But, it’s just that -one tool. Sometimes it’s insufficient. Sometimes, for various reasons, it’s not a good place to start.

Great summary of current evidence of resistance exercise for anxiety & depression -Understudied (overall & compared to aerobic) -Existing evidence + -Need larger, randomized studies -Need more studies w/ clinical disorders (instead of isolated symptoms or subclinical symptoms)

🚨We are hiring!🚨Assistant professor tenure-track position in exercise psychology (broadly defined) at ISU for fall ‘24. Come join a strong, federally-funded translational kinesiology dept in a very supportive environment! DMs open. Plz retweet! isu.wd1.myworkdayjobs.com/IowaStateJobs/…

Report finds growing number of kids prescribed multiple psych meds (despite lack of evidence for polypharmacy & safety concerns) Reminder: the evidence-based use of psych meds is cautious and judicious. Less is often more jamanetwork.com/journals/jaman…

Overview of ADHD medications (in order of their efficacy) up on my website today alliyoungmd.com/2025/10/01/adh…

Serial ketamine infusions not statistically significantly better than benzo control in treating depression inpatient. Questions prior promising saline-controlled trials. Important as ketamine use is increasing despite increasingly questionable efficacy jamanetwork.com/journals/jamap…

History and thoughtful critique of the DSM by Awais Aftab asteriskmag.com/issues/12-book…

When CBT is done well, it’s dynamic.

A breakdown of a recent systematic review and meta-analysis of the effects of ketogenic diets on depression and anxiety: alliyoungmd.com/2025/11/25/res…

A new Lancet Psychiatry meta-analysis finds stopping antidepressants “slowly” (>4 weeks) with support is as effective as staying on them. But it used an outdated definition, didn’t measure withdrawal, misclassified withdrawal as relapse, and used non-hyperbolic tapers. (1/n)

Such an important paper & public health call to action - Disease burden attributable to intimate partner violence against females and sexual violence against children 1990–2023. These are significant & modifiable social risk factors for mental disorders. thelancet.com/journals/lance…

Tailored Weight Loss Programs for Adults W/ Serious Mental Illness -included fitness app, fitness tracker, scale, & weekly support -# who lost 7% or more of body weight significantly higher for weight loss program; some other measures didn’t achieve sig jamanetwork.com/journals/jamap…

Antipsychotic tapering appears to help long-term in a new trial but not for the obvious reason… And considerable uncertainty remains My discussion of the HAMLETT study by Sommer et al. (October 2025, JAMA Psychiatry) psychiatrymargins.com/p/antipsychoti…

Looking forward to this documentary that highlights the massive scale of over-use of medication and potential alternative approaches

Just a PSA that the new dietary guidelines still recommend saturated fat be less than 10% of daily calories. Although red meat, cheese, and whole milk appear to be at the widest part of the pyramid, they still need to be eaten in moderation to keep saturated fat within the rec.

New scoping review in Schizophrenia Bulletin about methods of tapering antipsychotics finds "a move toward gradual and hyperbolic methods since 2020" bit.ly/49z4ab6