Holcman (@david_holcman) 's Twitter Profile
Holcman

@david_holcman

Brain predictions, Data analysis, Math, Neuroscience, Predictive anesthesia, EEG, modeling, Computational methods, Biophysics, Stochastic processes, algorithms

ID: 882180067870351360

linkhttps://www.ibens.ens.fr/spip.php?rubrique40&lang=fr calendar_today04-07-2017 10:11:33

213 Tweet

135 Followers

82 Following

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Workshop on Imaging, modelling, and statistical advances in quantitative neuropathology , quantitative neuroscience. IA, applied mathematics, statistics, and imaging to unravel cellular patterns in health and disease. oxforduniversitystores.co.uk/short-courses/…

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Tomorrow Modeling and computing of the extreme in cellular biology :An increasing number of questions in cell biology and biophysics can be framed as rare stochastic events. I will present computations, accelerate stochastic simulations, modeling on zoom math.univ-cotedazur.fr/node/23743

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Congratulation to Nathalie Rouach for her prize at the French Academy of Science 2024, received yesterday on her achievement on understanding of neuronal and glial Networks. cnrs.fr/fr/actualite/p…

Congratulation to Nathalie Rouach for her prize at the French Academy of Science 2024, received yesterday on her achievement on understanding of neuronal and glial Networks.

cnrs.fr/fr/actualite/p…
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Unraveling Microglial Spatial Organization in the Developing Human Brain with DeepCellMap, a Deep Learning Approach Coupled to Spatial Statistics: a new method to quantify spatio-temporal organization, @DavidMenassa1 Thibault Lagache Théo Perochon biorxiv.org/content/10.110…

Unraveling Microglial  Spatial Organization in the Developing Human Brain with DeepCellMap,  a Deep Learning Approach Coupled to Spatial Statistics:

a new method to quantify spatio-temporal organization, @DavidMenassa1 <a href="/StatBioImag/">Thibault Lagache</a> 
<a href="/PerochonTheo/">Théo Perochon</a> 
biorxiv.org/content/10.110…
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The computational and data modeling Neuroscience will continue in 2025 with T. Lagache on spatial statistics assisted by deep-learning youtube.com/playlist?list=…

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Unveiling the functional connectivity of astrocytic networks with AstroNet, a graph reconstruction algorithm coupled to image processing with Craig Zonca Nathalie ROUACH Rancillac Armelle 🔬 is now available nature.com/articles/s4200… thanks again to the Rouach's lab member

Unveiling  the functional connectivity of astrocytic networks with AstroNet, a  graph reconstruction algorithm coupled to image processing 
with <a href="/zonca/">Craig Zonca</a> <a href="/NathalieRouach/">Nathalie ROUACH</a>  <a href="/RancillacA/">Rancillac Armelle 🔬</a> 
is now available
nature.com/articles/s4200…
thanks again to the Rouach's lab member
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Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics nature.com/articles/s4146… Thanks to @DavidMenassa1 Thibault Lagache Théo Pérochon and all other contributors

Unraveling  microglial spatial organization in the developing human brain with  DeepCellMap, a deep learning approach coupled with spatial statistics
nature.com/articles/s4146…
Thanks to @DavidMenassa1 <a href="/StatBioImag/">Thibault Lagache</a>  <a href="/TheoPerochon/">Théo Pérochon</a> and all other contributors
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Congradulation to all for this Proof of Concept award. Our project "AnalysisSpectralEEG" presents new perpective to designa real-time AI algorithms to predict the brain especially during general anesthesia cnrs.fr/en/update/erc-…

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Remains a few place for IA-development meeting in Oxford March 14 2025 with. @DavidMenassa1 and T. Lagache Thibault Lagache oxforduniversitystores.co.uk/short-courses/…

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Topologically associating domains (TADs) compartmentalize genomes to limit enhancer–promoter loops. We report 3 main boundaries between TADs ranging from narrow to highly extended, modulating spurious long-range interactions (Coll. Daan noordermeer) pnas.org/doi/10.1073/pn…

Topologically associating domains (TADs) compartmentalize genomes to limit enhancer–promoter loops. We report 3 main boundaries between TADs ranging from narrow to highly extended,  modulating  spurious long-range  interactions (Coll. <a href="/Daannoordermee1/">Daan noordermeer</a>) 
pnas.org/doi/10.1073/pn…
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Interested in risk of cognitive decline How should clinicians interpret these results? journals.lww.com/ejanaesthesiol…

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Extremal Statistics in Biology is a challenging field of physics and applied math using data analysis, modeling and simulations, used to predict molecular organization and sub-cellular function. This week meeting in Vienna is dedicated to that topics esi.ac.at/events/e579/

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We identified subnetworks in the Cortex from 3D High-Density Two-Photon Calcium Imaging, revealing new computational organization. Thanks to Prevedel Lab and 浅利広樹 and P. Aymard and JC Boffi biorxiv.org/content/10.110…

We identified subnetworks in the Cortex from 3D High-Density Two-Photon Calcium Imaging, revealing new computational organization. Thanks to <a href="/Prevedel_Lab/">Prevedel Lab</a> and <a href="/hirokiasari/">浅利広樹</a> and P. Aymard and JC Boffi 
biorxiv.org/content/10.110…
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Assessing One-Dimensional Cluster Stability by Extreme-Point Trimming. A new statistical approach to classify stable clusters with E. Dereure E. Mfoumou arxiv.org/abs/2509.00258

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Toward an automated classification of lewis Body in Parkinson's disease :"Weakly Supervised Segmentation and Classification of Alpha-Synuclein Aggregates in Brightfield Midbrain Images", arxiv.org/abs/2511.16268 Thanks to all!

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Novel Method to classify similar trajectories from different cells and application to protein-protein interactions that drive differences in the spatiotemporal dynamics of transcription factors NANOG and SOX2 in naïve pluripotent cells biorxiv.org/content/10.648…