Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum | ⁦Nature Genetics⁩ nature.com/articles/s4158…

Efficacy and Safety of SGLT-2 Inhibitors in Patients With and Without Advanced CKD: Systematic Review and Meta-Analysis SGLT-2 inhibitors retain their kidney and cardiovascular protective effect in patients with advanced CKD with no added safety concerns journals.lww.com/cjasn/abstract…

Lp(a) levels not associated with cardiovascular or all cause death when LDL and CRP adjusted for. Is Lp(a) just a marker of risk or is it causal ? ahajournals.org/doi/full/10.11…

Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu Editorial:

Research suggests Clonal hematopoiesis of indeterminate potential (CHIP) may contribute to CKD and its comorbidities. This Review underscores the need for further research to identify the distinct pathways through which CHIP may contribute to CKD & its comorbidities.

#Clone size matter! Sharing our manuscript at Blood Neoplasia here ! Moffitt Cancer Center

Mentor, friend, and collaborator. Don’t let the pink dress fool you! Tireless, hard-working and brilliant physician-scientists and mom at the same time… Sad that I will be saying good bye to them in a month.. but collaboration will continue!!

🔥New Pub Haematologica 🔥 This was a multi-cntr study of #MPNsm with #echofirst from NYU Grossman School of Medicine & Mass General Cancer Center. We found an assoc between PH and heme progression. See below for a thread of our findings! #cardioonc haematologica.org/article/view/1…

🧵 1/ In high-dimensional bio data—transcriptomics, proteomics, metabolomics—you're almost guaranteed to find something “significant.” Even when there’s nothing there.

Increased risk of 13 different cancers with an elevated BMI NEJM #obesity