Got my visa to spend some time at Alex Compton in the NIH later this year! Super excited to visit the states and learn some cool techniques🤩 Thank you Microbiology Society for awarding me the research visit grant to support this project.

If Nelly Mak's project has inspired you to plan your own one- to three-month visit to another laboratory, visit our website to find out whether you're also eligible for our Research Visit Grant, which is open for applications: microb.io/2vS9B2x

The group at Tenth Ward Distilling Company, where we go when we have thoughts to distill. Welcome to the lab, Nelly Nelly Mak!

Now online at JCI Journal of Clinical Investigation, we show that mTOR inhibitors promote cell entry of SARS-CoV2☣️and exacerbate viral disease. A great collaboration between NCI NCI Center for Cancer Research, NIAID jon yewdell Sonja Best and OSU Jacob Yount! #SARSCoV2 #COVID19 jci.org/articles/view/…

Researchers NCI HIV Dynamics and Replication Program discover how a common treatment for cancer increases vulnerability to viral infection & identified an FDA-approved alt that could effectively treat cancer w/o weakening immune response to viral infection in this #CCRAdvance jci.org/articles/view/…

Researchers may have found a way to effectively treat cancer without weakening immune response to viral infection

The fourth Special Issue of 2022 was "The Multifaceted Innate Response to Virus Infection" guest edited by Alex Compton National Cancer Institute. See the whole collection of research articles and reviews here: bit.ly/37rI1yP

Call for papers: if you have an idea or a story in progress on the topic of IFITM proteins, submit your manuscript to our Special Issue in Viruses Viruses MDPI (edited by myself and Chen Liang, McGill University). Tentative submission deadline is October mdpi.com/journal/viruse…

🔔My first manuscript is on bioRxiv!🦇Chinese horseshoe bats not only have antiviral IFITMs, they also generate IFITM diversity by alternative splicing which is distinct from the human IFITM family. #InnateImmunity #LoveVirology biorxiv.org/content/early/… 🧵1/7

Omicron Spike confers enhanced infectivity and interferon resistance to #SARSCoV2 in human nasal tissue Alex Compton nature.com/articles/s4146…

Interested in the intersection between SNARE fusion machinery and innate immunity? The latest preprint from the lab is posted while it's being peer-reviewed: SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion biorxiv.org/content/10.110…