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After ~10 years of work, feeling very proud/grateful to have had our work on Thrombosis & Atherosclerosis published in Circulation this month! PK Saha Clemens Gutmann King's College London Venous Thrombosis Accelerates Atherosclerosis in Mice | Circulation ahajournals.org/doi/10.1161/CI…

An impressive trio of papers makes a strong case for platelet factor 4 (PF4) as the key to reducing inflammation and improving cognition in the aged brain model nature.com/articles/s4158… nature Villeda Lab UCSF School of Medicine @justsaysinmice

Super thrilled to share our most recent work, published today in nature! Adam Schroer and Brit Ventura led this tour de force study, which shows that a platelet factor in blood plasma – PF4 – can attenuate inflammation and rescue cognition in aging: nature.com/articles/s4158…

Congrats Isabella Ragone !🎉🎉🎉

Longevity factor klotho – like exercise – activates platelets which release PF4. PF4 permeates the brain to increase synaptic plasticity and enhance cognition in young and aging mice. By my group UC San Francisco nature.com/articles/s4358… Nature Aging Cana Park

Effect of #Alirocumab Added to High-Intensity #Statin on Platelet Reactivity and Non-coding RNAs in #ACS pubmed.ncbi.nlm.nih.gov/37595625/

One man's niche is another man's treasure 😀

Wow! Microplastics and Nanoplastics in Carotid Plaque Increases Cardiovascular Events 4.5 Fold | NEJM nejm.org/doi/pdf/10.105…