It’s normal (pun?) for a bioassay to have a geometric standard deviation of 2-3 fold. This informs my earlier comment saying that an IC50 of 10 nM and 30 nM aren’t really different from one another and shouldn't be used for decision-making. 19/ x.com/KRHornberger/s…

In environments sequestered from bulk solvent, electrostatic modeling is its worst.

Starting your car after a LONG break there is always an anxious moment when you’re unsure if it’s going to start up again. Science can feel the same way. But, like your car, all you may need is a jumpstart eg. a nice science chat or reading a great paper. What’s your jumpstart?

Happy New Year BE-STEM Family! We are back for our first General Meeting of 2023 on Wednesday, January 18th from 6-7pm in MH-1105 or via zoom! Register using the link below to receive location/zoom: cglink.me/2c7/r1954338

Last week I was fortunate to speak with students at KIPP-SFCP with the Bay Area Youth Sciences (BAYS) program UC San Francisco. Had a great time discussing immunity during respiratory illness. They were so inquensitive and eager to learn. Highlight of my week! #STEMeducation

How many PIs out there miss the brief moment of being the first and only person in the world to know a bit of new biology?

I hate when I hear people say, “racism is a hard conversation to have”. For who?!

Want to learn how #languagemodels are reshaping drug discovery? Check out my minireview in Current Opinion/Research in Structural Biology, exploring chemical language models for de novo drug design, their limitations, and opportunities ahead: authors.elsevier.com/sd/article/S09… #ML #AI #ChemTwitter #Drugdiscovery

I'm creating 3D tours of open single cell RNA-seq data in UMAP space. Here, using data from 50k brain cells by the Allen Institute . (portal.brain-map.org/atlases-and-da…). The UMAP position and class of every cell is read into Blender, realized as a stylized, class-specific model I sculpted

A bit of a late post but excited to start accepting applications for the 3rd cohort of UCSF BAYS Scholars. We were recently highlighted in UCSF News! pharmacy.ucsf.edu/news/2023/02/c…

Happy to share our latest paper Neuron, in collaboration with the labs of Victoria E. Abraira Ewan St. John Smith The Yttri Lab. "Mapping the neuroethological signatures of pain, analgesia, and recovery in mice" sciencedirect.com/science/articl…

It’s gonna be times when you feel discouraged, fight through it and never give up. You’re doing good.

Congrats to the 3rd cohort of UCSF BAYS Scholars !! A wonderful collaboration of many stakeholders at ucsf, this year championed by the prolific Trase Aguigam and Sydney Williams! S/o to Emma Gunderson for administrative support! So proud of the scholars and the team!

What wonderful news! Thank you Biophysical Society for recognizing #BlackExcellence in #biophysics. With this platform the Black In Biophysics community will undoubtedly grow in the years to come and the next generation of Black biophysicists will feel represented and valued in the field

🚨 Update for INRC 2024 🚨 Dr. Howard Fields will be giving the Founder's Lecture at INRC 2024. He will showcase his brilliant and groundbreaking discoveries at UC San Francisco in the substance abuse and pain fields. Not one to miss! Join us in Ann Arbor, MI July 9-12!

Did you miss the UC San Francisco Byers Award Lecture in Basic Science, featuring Aashish Manglik? Watch the recording here! tiny.ucsf.edu/2ODQNM mangliklab.com pbbr.ucsf.edu michael gropper

How do cells communicate? UCSF's Aashish Manglik explored cellular communication through specialized protein receptors at the 29th annual Byers Award Lecture. UCSF School of Pharmacy tiny.ucsf.edu/MAnu3P

Top 4 things to know about doing science: 1. You need to have someone you can talk to 2. One-on-one discussions are the best 3. Think about discussions as improvisations and use the ‘yes, and’ rule 4. Create a safe space so both of you feel open to saying seemingly silly things