Hot off the press in IJROBP - The Red Journal: the ARREST phase I trial of SABR in poly-metastatic disease, led by Glenn Bauman, MD & Tim Nguyen Average number of lesions = 16 Dose safely escalated to 30 Gy in 5 fractions. sciencedirect.com/science/articl… The phase II/III RCT ARREST2 is underway!

🔥Hot off the press European Urology Oncology IROCK 🇨🇦🇦🇺🇺🇸🇩🇪🇯🇵 demonstrating #SABR ⚡️yields moderate long-term renal function decline, low dialysis rates even in patients with a solitary kidney #radonc authors.elsevier.com/c/1jOzs9Cfv--d… Thankful for mentors Shankar Siva Alex Louie MD, PhD Rohann Correa

Generating 3D images of VMAT plans for predictive models and activation maps associated with plan deliverability #Yonsei #MP🇰🇷 American Association of Physicists in Medicine pubmed.ncbi.nlm.nih.gov/38978162/

Pooled analysis of Korea and Italy by kyubo.kim. Great job! 👏Raises important questions about the potential interaction for RN between T-DM1 and SRS. But it's still unclear if T-DM1 needs to be discontinued around SRS or if it has no effect.🤔

Addition of Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma (EXTEND): A Multicenter, Randomized Phase II Trial | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…

Prospective study showing no difference in cosmetic outcome with hypofractionation for PMRT and implant #bcsm ⁦Chirag Shah⁩ ⁦Erin Gillespie, MD MPH⁩ jamanetwork.com/journals/jamao…

🎙 2 CTH cycles less do not compromise the results w/ a ⬆️ CR-R 🟰RAPIDO trial ❗️OncoAlert The Lancet Oncology 📌Methods * 👥: high-risk locally advanced #rectalcancer (LARC). * Study design: Prospective observational cohort study. * Treatment: Short-course ☢️➡️4 CAPOX or 6

The EXTEND 🪜 #Ph2 trial in Journal of Clinical Oncology show that adding metastasis-directed therapy (MDT) to 💉 ⬆️ #PFS in oligometastatic #pancsm suggesting systemic immunity 🛡️as a potential mechanism. #GIonc OncoAlert🚨 Elisabetta Bonzano MD, PhD Gil Morgan, MD Aakash Desai, MD, MPH ascopubs.org/doi/10.1200/JC…

📌 PRECISE: Preoperative Radiotherapy to Elicit Critical Immune Stimulating Effects – A Phase II Clinical Trial pubmed.ncbi.nlm.nih.gov/39147206/ 👉🏻Stromal TIL increased 6-8 days following completion of boost radiotherapy (median 3.0 (IQR 1.0-6.5) prior to radiotherapy vs. median 5.0 (IQR

Randomized phase II STOP trial of SBRT for oligoprogressive cancer - 127 pts - 3.4% G3 tox, no G4/5 tox - No difference in PFS: median 8.4mo (SBRT) vs 4.3 mo (SoC) - HOWEVER, protocol adherence suboptimal, 35% in SoC treated with SBRT or study withdrawal redjournal.org/article/S0360-…

Beyond 2 years, 86% of patients on the standard arm had received RT, either SABR or conventional. So if we don't deliver SABR at the time of oligoprogression, we'll probably be delivering some kind of RT later.

Just out @JACC CardioOncol, we intricately map #radiation exposure from #radiotherapy for #LCSM to different sub-structures of the heart to predict the risk of 5 different classes of #cardiac arrhythmias, pointing to possibly distinct pathophys pathways. sciencedirect.com/science/articl…

Nice paper and highlight an important point about intrafraction motion during breast RT. Intrafraction motion in surface-guided breast radiotherapy, and its implications on a single PTV margin strategy practicalradonc.org/article/S1879-…

📌 Residual breast tissue after mastectomy and reconstruction: A substudy of the Spatial location of breast cancer local rECurRence aftEr masTectomy (SECRET) project 👉🏻 Different mastectomy procedures vary according to technique and extent of tissue removed. 👉🏻 The amount of

With a median BED10 of 105 Gy and an LR rate of 33% after SBRT, findings indicate that CRC metastases may require higher doses for improved local control, aligning with other studies in the field. We conducted a very similar study—hoping it gets accepted and published soon!

Organ preservation after neoadjuvant long-course chemoradiotherapy versus short-course radiotherapy - Annals of Oncology annalsofoncology.org/article/S0923-…

8 Gy single fx liver RT + BSC improves liver pain control compared to BSC in painful hepatic cancer: the CCTG HE1 trial thelancet.com/journals/lanon…

☢️ Systematic review and meta-analysis of SABR in oligoprogression published in Radiotherapy & Oncology authors.elsevier.com/c/1jkuTcA0-IX1E Joelle Dr. David Palma Aisling Barry Jacques Raphael

A shocking image....😵