
Carlos Cruchaga
@ccrugom
NeuroGenomics and Informatics Center Director.
Washington University School of Medicine
ID: 481753989
https://cruchagalab.wustl.edu 03-02-2012 04:17:21
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Our ability to accurately predict #Alzheimer's disease years in advance of any symptoms keeps getting better with plasma proteins and A.I. analytics Nature Aging nature.com/articles/s4358…


🚨Preprint Alert!!!! Fantastic manuscript from the team!! Aleksandra Beric Carlos Cruchaga We explored whole blood transcriptome and nominated some genes and early biomarkers. #Parkinson #transcriptomics Thanks to michaeljfox.org for the support! Link below👇📷👇 medrxiv.org/content/10.110…

Around 5-10% of the #Alzheimers cases are early-onset, and are understudied. In a multiancestry genetic study of Early-onset AD we identified eight novel genes that point to dysregulation of glutamate, immune activation WashU Medicine Knight ADRC WashU Medicine Neurology alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…


The first four papers mining the GNPC proteomics dataset surfaced plasma signatures of cognitive decline and neurodegeneration, and a pro-inflammatory profile in APOE4 carriers. #alzheimers #parkinsons #FTD @wustl Stanford University University of Oxford University of Sydney ow.ly/Qnwt50WuxQR
