End of an era - sad to say farewell to Kailin after his time with us as a Cleveland Clinic Lerner College of Medicine medical student & #radonc resident - best wishes on your new adventure in University of Iowa - see you soon! Looking forward to many collaborations continuing! Jake Scott Omar Mian Andrew Dhawan

This week in MathOnco 299... Spatial evolution, patient-specific models, EMT, plasticity and more... Art: based on Jeff Maltas & Jake Scott's PRX Life cover Signup: mathematical-oncology.org/newsletter

we are getting noticed... 😍

Unlocking the mystery of preexisting #drugResistance: Study sheds light on #cancer evolution PRX Life medicalxpress.com/news/2024-07-m…

This remarkable study essentially validated our earlier finding in ALK+ NSCLC with Robert Vander Velde and Jake Scott that resistance is acquired through a trajectory rather than a switch nature.com/articles/s4146….

Nice summary of our recent work in #lungcancer #evolution and #gametheory News release: eurekalert.org/news-releases/… Original paper: journals.aps.org/prxlife/abstra… Cleveland Clinic Lerner Research Institute OncoAlert IMO Mathoncoblog CWRU Physics CWRU School of Medicine PRX Life

Machine Learning to predict the outcome of radiotherapy 👉 results from Medical Research Council funded S:CORT consortium #cancerresearch #trascriptomics #precisionmedicine #machinelearning #omics 👀 more to come watch this space 👀 University of Oxford Università Bocconi ➡️ 🔗 sciencedirect.com/science/articl…

☢️Phase 2 trial shows celiac plexus radiosurgery offers promising pain relief for advanced cancer. ☢️Among 125 patients with upper GI cancers, 53% experienced partial pain relief at 3 weeks post-treatment with a single 25 Gy dose. ☢️Common side effects were abdominal pain (28%)

Interested in the evolution of drug resistance? Or working with animal models & clinical data to implement new a Centre for Evolutionary Therapy for NSCLC? The #AndersonLab is hiring a postdoc to work in IMO on our NCI Systems Biology U54: The Delta Ecology of NSCLC. More here: labpages.moffitt.org/andersona/jobs…

#Evo2024 Tomorrow! Come to my talk on mutators, multidrug resistance evolution and evolutionary rescue. 516B at 9:30 Tues 30 July in the Evolutionary Rescue Symposium.

Is there more than one mechanism underlying resistance to an antifungal drug? How many mechanisms are there? Kara Schmidlin and Sam Apodaca explore these questions in their paper out today in final form at eLife - the journal! elifesciences.org/articles/94144 (1/9)

Really interesting new collateral sensitivity study with barcoding and lineage tracking!

We’re launching Vironexis Biotherapeutics today, unveiling our TransJoin #AAV #GeneTherapy Platform, a pipeline of 10+ product candidates, and FDA clearance of our IND for the 1st-ever clinical trial of an AAV-delivered #cancer #immunotherapy. Learn more: bit.ly/3MDXzB4

Great article by Elizabeth Eaton in FirstWord Pharma about our platform technology, pipeline and mission to transform cancer treatment for patients with AAV-delivered T-cell immunotherapy! See article: firstwordpharma.com/story/5894733

Exciting time in Oncology. Startup Vironexis Biotherapeutics brings new crossover paradigm: gene therapy to make in vivo bites! endpts.com/cancer-gene-th…

Thank you ⁦Navneet Majhail, MD, MS⁩ for coming back home ⁦Cleveland Clinic⁩ for the Cancer Center for an excellent grand rounds!! ⁦Christopher Wee, MD⁩

Great story on our new Vironexis Biotherapeutics programmable #genetherapy platform to create lifelong t-cell engaging bispecific antibodies from a single infusion - from Medium OncoAlert OncoDaily Medscape Oncology Nationwide Children's Hospital medium.com/leadership-pre…

What a compelling essay. Thank you Craig for being will to share your personal story.

Omar Mian Cleveland Clinic Cleveland Clinic Lerner Research Institute Fred Hutchinson Cancer Center University of Washington Radiation Oncology Jake Scott Rahul Tendulkar, MD Shilpa Gupta Chirag Shah Timothy Chan Kevin Stephans MD Erin Murphy MD Babal Jha Yogen Saunthararajah Congratulations Omar Mian on becoming the Precision Radiation Science Lead at University of Washington Radiation Oncology Fred Hutchinson Cancer Center! 🙏 for your many contributions to patient care, education and research Cleveland Clinic MD #radonc #CleClinicCancer.! We wish you the very best! Ramesh Rengan

Ayesha Gonzales, Brandon Shipley, Prof Michael Hinczewski (@HinczewskiLab), & collaborators from CWRU Engineering published "Motion blur microscopy: in vitro imaging of cell adhesion dynamics in whole blood flow" in Nature Communications 👏 Full text: nature.com/articles/s4146…