Brian Sigafoos (@briansigafoos) 's Twitter Profile
Brian Sigafoos

@briansigafoos

Techno-optimist. “Win and help win” context engineer, 2x founder. e/acc

ID: 82599998

linkhttps://briansigafoos.com calendar_today15-10-2009 11:58:59

8,8K Tweet

641 Followers

2,2K Following

Brian Halligan (@bhalligan) 's Twitter Profile Photo

NEW EPISODE: jack & Roelof Botha unpack Block 40% staff cut and rebuilding the entire company as a mini-AGI. This isn’t “use AI to make people more productive.” It’s making the company itself the intelligence. If you’re a founder or operator wondering what work looks like in

Jordi Hays (@jordihays) 's Twitter Profile Photo

TBPN has been acquired by OpenAI The world is changing quickly but TBPN will stay the same. Live every weekday just with a lot more resources. Thank you to everyone that has been a part of this journey big or small. We are 17 months in and unironically just getting started.

TBPN has been acquired by OpenAI

The world is changing quickly but TBPN will stay the same. Live every weekday just with a lot more resources.

Thank you to everyone that has been a part of this journey big or small. We are 17 months in and unironically just getting started.
Zoomer (@zoomyzoomm) 's Twitter Profile Photo

< Be John Coogan < co-founded Soylent and Lucy nicotine pouches as a serial entrepreneur in consumer tech. <built a career as a veteran YouTuber < worked as an EIR at Founders Fund. < meet Jordi Hays through mutual friend Will Manidis in 2023. < instantly bond over their

&lt; Be John Coogan  
&lt; co-founded Soylent and Lucy nicotine pouches as a serial entrepreneur in consumer tech.  
&lt;built a career as a veteran YouTuber 
&lt; worked as an EIR at Founders Fund.  
&lt; meet Jordi Hays through mutual friend Will Manidis in 2023.  
&lt; instantly bond over their
jack (@jack) 's Twitter Profile Photo

"In practice, Spectre is the beginning of a company world model: a live picture of what is happening inside Harvey and what needs to happen next." harvey.ai/blog/autonomou…

Will Ahmed (@willahmed) 's Twitter Profile Photo

You have no experience. You’ve never started a company. You’ve never had a full time job. Nike is going to kill you. You’re a kid. You don’t have technical skills. You shouldn’t build hardware. Apple is going to kill you. You can’t build hardware. You can’t measure heart

You have no experience. 
You’ve never started a company. 
You’ve never had a full time job. 
Nike is going to kill you. 
You’re a kid. 
You don’t have technical skills. 
You shouldn’t build hardware. 
Apple is going to kill you. 
You can’t build hardware. 
You can’t measure heart
Chubby♨️ (@kimmonismus) 's Twitter Profile Photo

1/ Insane: A single injection into the inner ear reversed deafness in all ten patients. Some started hearing again within weeks. Gene therapy just crossed a threshold we thought was still years away. Lets dig into this breakthrough and how it works 🧵

1/ Insane: A single injection into the inner ear reversed deafness in all ten patients. Some started hearing again within weeks. Gene therapy just crossed a threshold we thought was still years away.

Lets dig into this breakthrough and how it works 🧵
Andrej Karpathy (@karpathy) 's Twitter Profile Photo

Wow, this tweet went very viral! I wanted share a possibly slightly improved version of the tweet in an "idea file". The idea of the idea file is that in this era of LLM agents, there is less of a point/need of sharing the specific code/app, you just share the idea, then the

Peter Yang (@petergyang) 's Twitter Profile Photo

Why OpenAI doesn't focus on roadmaps from Alexander Embiricos (Codex product lead): "At OpenAI, you either plan near or long-term, but you never plan medium-term. It's just too difficult. Near-term is up to eight weeks from now. What is a concrete thing you can rally a team to ship?

Chubby♨️ (@kimmonismus) 's Twitter Profile Photo

Holy moly: Sam Altman told Axios in a half-hour interview that AI superintelligence is so close, so mind-bending, so disruptive that America needs a new social contract. - It's on the scale of the Progressive Era in the early 1900s, and the New Deal during the Great Depression.

Holy moly: Sam Altman told Axios in a half-hour interview that AI superintelligence is so close, so mind-bending, so disruptive that America needs a new social contract.

- It's on the scale of the Progressive Era in the early 1900s, and the New Deal during the Great Depression.
Sriram Krishnan (@sriramk) 's Twitter Profile Photo

Having your computer run overnight on a task and then checking on it in the morning is one of the best feelings in tech. When I was a kid it was doing a multi part download or a slow running task. Now it is to run a harness / agent loop / something GPU bound overnight.

John Kraus (@johnkrausphotos) 's Twitter Profile Photo

The Artemis II crew's Earthset and eclipse images are now on images.nasa.gov in full resolution: Earthset: images.nasa.gov/details/art002… Captured with a Nikon D5 and Nikon 80-400mm f/4.5-5.6 at 400mm, 1/1000, f/8, ISO 400 Eclipse: images.nasa.gov/details/art002… Captured with a

The Artemis II crew's Earthset and eclipse images are now on images.nasa.gov in full resolution:

Earthset: images.nasa.gov/details/art002…

Captured with a Nikon D5 and Nikon 80-400mm f/4.5-5.6 at 400mm, 1/1000, f/8, ISO 400

Eclipse: images.nasa.gov/details/art002…

Captured with a
Marques Brownlee (@mkbhd) 's Twitter Profile Photo

Ok last one: the rarest solar eclipse of all time. Only 4 people have seen this with their naked eyes. The sun is fully behind the moon. The only faint light hitting the near side is reflecting off of earth, 250,000 miles away. And the stars and galaxies in the background, sheesh

Ok last one: the rarest solar eclipse of all time. Only 4 people have seen this with their naked eyes. The sun is fully behind the moon. The only faint light hitting the near side is reflecting off of earth, 250,000 miles away. And the stars and galaxies in the background, sheesh
NASA (@nasa) 's Twitter Profile Photo

Hello, Moon. It’s great to be back. Here’s a taste of what the Artemis II astronauts photographed during their flight around the Moon. Check out more photos from the mission: nasa.gov/artemis-ii-mul…

Hello, Moon. It’s great to be back.
 
Here’s a taste of what the Artemis II astronauts photographed during their flight around the Moon. Check out more photos from the mission: nasa.gov/artemis-ii-mul…
Anthropic (@anthropicai) 's Twitter Profile Photo

Introducing Project Glasswing: an urgent initiative to help secure the world’s most critical software. It’s powered by our newest frontier model, Claude Mythos Preview, which can find software vulnerabilities better than all but the most skilled humans. anthropic.com/glasswing

Chubby♨️ (@kimmonismus) 's Twitter Profile Photo

Let that sink in. Read it very carefully: During testing, Claude Mythos Preview broke out of a sandbox environment, built "a moderately sophisticated multi-step exploit" to gain internet access, and emailed a researcher while they were eating a sandwich in the park.

Let that sink in. Read it very carefully:

During testing, Claude Mythos Preview broke out of a sandbox environment, built "a moderately sophisticated multi-step exploit" to gain internet access, and emailed a researcher while they were eating a sandwich in the park.
Marc Andreessen 🇺🇸 (@pmarca) 's Twitter Profile Photo

Every security flaw discovered by AI was there before AI, waiting to be discovered either by people or by AI. The world has never been good at securing computer systems; finally with AI we are going to get good.

Andrew McCarthy (@ajamesmccarthy) 's Twitter Profile Photo

I knew the photos would be good I knew they would enhance my perception of the universe and inspire me I still completely underestimated them

I knew the photos would be good

I knew they would enhance my perception of the universe and inspire me

I still completely underestimated them
Tenobrus (@tenobrus) 's Twitter Profile Photo

maybe this is not yet clear, so let me state it plainly: as of right now Anthropic, and really a small number of individuals at Anthropic, has the capacity to directly attack and cause major damage to the United States Government, China, and generally global superpowers.

maybe this is not yet clear, so let me state it plainly: as of right now Anthropic, and really a small number of individuals at Anthropic, has the capacity to directly attack and cause major damage to the United States Government, China, and generally global superpowers.
GoPro (@gopro) 's Twitter Profile Photo

The most historic #GoPro images ever captured. Slide 1: The Moon, seen backlit by the Sun during a solar eclipse on April 6, 2026, is photographed by a GoPro on the Orion spacecraft’s solar array wing. Orion is visible in the foreground on the left. Earth is reflecting sunlight

The most historic #GoPro images ever captured.

Slide 1: The Moon, seen backlit by the Sun during a solar eclipse on April 6, 2026, is photographed by a GoPro on the Orion spacecraft’s solar array wing. Orion is visible in the foreground on the left. Earth is reflecting sunlight