I’m pleased to share my Commentary on the newly published *positive trial* finding metformin decreased Long Covid (Dr. Carolyn Bramante + ⁦Dr. David B⁩)! The therapeutic validation of long COVID. Lancet Infectious Diseases ⁦The Lancet Infectious Diseases⁩ thelancet.com/journals/lanin…

New research: Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial thelancet.com/journals/lanin…

LONG COVID: Really important study. Randomized. Metformin easily accessible treatment usually for diabetes (low-cost-safe)- Outpatient treatment with metformin x 14 days reduced long COVID incidence by about 41%compared with placebo; take within 3 days thelancet.com/journals/lanin…

“The results of this study are important because #LongCOVID can significantly impact people's lives,” said #UMNMedicine professor Dr. Carolyn Bramante. “#Metformin as a preventive measure could have significant public health implications." Read more: mprnews.org/story/2023/06/…

“The phase 3 trial — considered the gold standard in research — revealed that metformin could reduce the risk of #LongCovid by up to 63% among participants who started treatment within four days of their initial COVID diagnosis.” sfchronicle.com/health/article…

This is absolutely groundbreaking. Amphotericin B that is both oral and less toxic. Maybe the most important advance in the antifungal field since the introduction of echinocandins and mold active azoles. academic.oup.com/cid/article/do…

If you thought the burden of #LongCovid was mainly in high income countries, think again thelancet.com/journals/lance… H/T @Daltmann10 The Lancet by Waasila Jassat and colleagues

So grateful to be part of the amazing team of authors from The Obesity Society Society of General Internal Medicine (SGIM) American Board of Obesity Medicine NYU General Internal Medicine for this review. Check out the podcast as well!

Great work! Jessica Schwartz Carolyn T. Bramante, MD, MPH @gudzune

A computer simulator developed by Prof. David Odde & team was used in a phase 3 randomized clinical trial published in Clinical Infectious Diseases. David Odde Lab U of M Research College of Sci & Eng

Here’s the story with link to the CID article.

SO HAPPY the Johns Hopkins GIM fellowship family is back together at #SGIM24!!! 💙💛 #BMorePride SGIM

Congratulation!! So well deserved!

I got COVID19 a few weeks ago and based on the clinical trial data in support of metformin being able to lower the risk of long COVID, I decided to take a 2-week course. My COVID symptoms improved rapidly & 🤞 long COVID risk should be about 41% reduced… thelancet.com/journals/lanin…

Please join us on Wednesday, Sept. 25th at Noon for our next #medicalgrandrounds ! We will be joined by Carolyn T. Bramante, MD, MPH from UMN Medicine ! #northwestern #northwesternmedicine #nmim #COVIDー19 #Covid_19

Congratulations to #HopkinsGIM faculty Dr. Chidinma Ibe!

#IDWeek2024, I am excited to present: "578 - Metformin reduces the risk of Long COVID or Death over 6 months in an Emulated Target Trial of Primarily Omicron-infected Adults without Diabetes or Prediabetes: a New-User, Active-Comparator Analysis Using the National COVID Coho...