
Blurton-Jones Lab
@blurtonjoneslab
#Neuroimmunology lab @UCIrvine studying the role of #microglia in #Alzheimer’s disease and developing #iPSC-microglia based therapeutic approaches
ID: 1012827881305567233
https://faculty.sites.uci.edu/blurtonjoneslab/ 29-06-2018 22:39:19
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We are excited to share new paper led by the talented Nicole Scott-Hewitt that a microglial C1q, can be internalized by neurons in the healthy aging brain, undergoes liquid-liquid phase separation (LLPS), integrates into neuronal RNPs and impacts neuronal proteostasis 1/3

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease Nature Medicine nature.com/articles/s4159…

Another tour de force from Oleg Butovsky lab further expanding our understanding of the APOE biology in Alzheimer’s disease. Congrats to the entire team of authors!

Blurton-Jones Lab ButovskyLab NetaRosezweig @KilianKleemann Bart Eggen Howard L. Weiner, MD Roni Nowarski Thanks, Matt! Very excited to continue our collaboration. I hope to see our work on Xe coming soon to light😜

APOE4-dependent neutrophil-microglia interactions drive cognitive impairment in female individuals with Alzheimer’s disease via IL17F ButovskyLab, Oleg Butovsky, NetaRosezweig, @KilianKleemann #neutrophils, #microglia, #IL-17 nature.com/articles/s4159…


Thank you Alzheimer Society of Canada for promoting the work we recently completed on human CD33 isoforms in Alzheimer’s disease. Beyond grateful for the support to myself and research in @MatthewMacaule4 lab, and super proud to be an ASRP funded fellow. alzheimer.ca/en/whats-happe…



So excited to be part of the new VCID Center Without Walls for Understanding and Leveraging Small Vessel Cerebrovascular Disease Mechanisms in ADRD. Looking forward to working with our team Andrew C. Yang Julie Schneider Blurton-Jones Lab and Yadong Huang Gladstone Institutes Rush Alzheimer's Disease Center


Celeste Karch we are looking forward to your presentation at #TargetAD25 in Crete next May🇬🇷☀️Registration & Talk Submission is now OPEN so please RT to let your followers know! Find out more: bit.ly/3zOJ0Y1




More excellent work from the brilliant Lynn van Olst. I’m a very proud PI today. More to come from Abrams Research Center on Neurogenomics!


This amazing news made my week! 🎊 I’m beyond blessed to be part of the BrightFocus Foundation community while studying the protective microglial responses in the context of Alzheimer’s disease. Super thankful to Blurton-Jones Lab and the entire MBJ team for their continuous support!


We are excited to share our newest publication from the Blurton-Jones Lab, "Harnessing human iPSC-moceoglia for CNS-wide delivery of disease modifying proteins." sciencedirect.com/science/articl…


Congratulations to Jean Paul Chadarevian and the whole Blurton-Jones team for this beautiful piece of work: Harnessing human iPSC-microglia for CNS-wide delivery of disease modifying proteins." 👍👍👍
