Blurton-Jones Lab (@blurtonjoneslab) 's Twitter Profile
Blurton-Jones Lab

@blurtonjoneslab

#Neuroimmunology lab @UCIrvine studying the role of #microglia in #Alzheimer’s disease and developing #iPSC-microglia based therapeutic approaches

ID: 1012827881305567233

linkhttps://faculty.sites.uci.edu/blurtonjoneslab/ calendar_today29-06-2018 22:39:19

250 Tweet

2,2K Followers

1,1K Following

beth stevens (@stevens1lab) 's Twitter Profile Photo

We are  excited   to share new paper led by the talented Nicole Scott-Hewitt that a microglial C1q, can be  internalized by neurons in the healthy aging brain, undergoes liquid-liquid phase separation (LLPS), integrates into neuronal RNPs and impacts neuronal proteostasis 1/3

John Lukens (@lukensjohnr) 's Twitter Profile Photo

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease Nature Medicine nature.com/articles/s4159…

Ghazaleh Eskandari-Sedighi (@ghazalehesk) 's Twitter Profile Photo

Another tour de force from Oleg Butovsky lab further expanding our understanding of the APOE biology in Alzheimer’s disease. Congrats to the entire team of authors!

Nature Medicine (@naturemedicine) 's Twitter Profile Photo

APOE4-dependent neutrophil-microglia interactions drive cognitive impairment in female individuals with Alzheimer’s disease via IL17F ButovskyLab, Oleg Butovsky, NetaRosezweig, @KilianKleemann #neutrophils, #microglia, #IL-17 nature.com/articles/s4159…

Jenn Orthmann Murphy (@jennoligomyelin) 's Twitter Profile Photo

Important paper on prevalance of CSF1R variants - congrats to David Lynch and colleagues CSF1R-Related Disorder | Neurology Genetics neurology.org/doi/10.1212/NX…

Ghazaleh Eskandari-Sedighi (@ghazalehesk) 's Twitter Profile Photo

Thank you Alzheimer Society of Canada for promoting the work we recently completed on human CD33 isoforms in Alzheimer’s disease. Beyond grateful for the support to myself and research in @MatthewMacaule4 lab, and super proud to be an ASRP funded fellow. alzheimer.ca/en/whats-happe…

Dr. Elizabeth Head (@elzhead) 's Twitter Profile Photo

We hope this helps with clinical trial design for people with Down syndrome. Very much enjoyed this productive collaboration!

Gan Lab (@liganlab) 's Twitter Profile Photo

We're excited for our latest work published in @Neuron! We explored the impact of Alzheimer's risk factors APOE4 and TREM2-R47H in a tauopathy mouse model, revealing elevated microglial cGAS-STING signaling and senescence in females with both risk factors. cell.com/neuron/fulltex…

MRIIT (@mriatiit) 's Twitter Profile Photo

So excited to be part of the new VCID Center Without Walls for Understanding and Leveraging Small Vessel Cerebrovascular Disease Mechanisms in ADRD. Looking forward to working with our team Andrew C. Yang Julie Schneider Blurton-Jones Lab and Yadong Huang Gladstone Institutes Rush Alzheimer's Disease Center

Ghazaleh Eskandari-Sedighi (@ghazalehesk) 's Twitter Profile Photo

Beyond grateful to the Larry L. Hillblom foundation for supporting my postdoctoral research ⁦UCI MIND⁩ big thanks to ⁦Blurton-Jones Lab⁩ and our amazing lab members for their tremendous help and support with this project! llhf.org/portfolio/ghaz…

Fusion Conferences (@fusion_conf) 's Twitter Profile Photo

Celeste Karch we are looking forward to your presentation at #TargetAD25 in Crete next May🇬🇷☀️Registration & Talk Submission is now OPEN so please RT to let your followers know! Find out more: bit.ly/3zOJ0Y1

<a href="/karchlab/">Celeste Karch</a> we are looking forward to your presentation at #TargetAD25 in Crete next May🇬🇷☀️Registration &amp; Talk Submission is now OPEN so please RT to let your followers know! 
Find out more: bit.ly/3zOJ0Y1
Mariko Bennett MD PhD (she/her) (@nachoriko) 's Twitter Profile Photo

On this #RareDiseaseDay2025 , we cannot remain silent. We must fight on the beach, and on the bench. Call your elected officials, call those who weren't elected who have become our officials. It is not "saving" us money, it is costing us our future. #fightonthebench

On this #RareDiseaseDay2025 , we cannot remain silent. We must fight on the beach, and on the bench. Call your elected officials, call those who weren't elected who have become our officials. It is not "saving" us money, it is costing us our future. #fightonthebench
David R. Liu (@davidrliu) 's Twitter Profile Photo

“It is hard to put into words the extent of the damage being done to the US research enterprise, which is of almost incalculable value to both the nation itself and the wider world… An assault on science and scientists anywhere is an assault on science and scientists

Ghazaleh Eskandari-Sedighi (@ghazalehesk) 's Twitter Profile Photo

This amazing news made my week! 🎊 I’m beyond blessed to be part of the BrightFocus Foundation community while studying the protective microglial responses in the context of Alzheimer’s disease. Super thankful to Blurton-Jones Lab and the entire MBJ team for their continuous support!

This amazing news made my week! 🎊 I’m beyond blessed to be part of the <a href="/_BrightFocus/">BrightFocus Foundation</a>  community while studying the protective microglial responses in the context of Alzheimer’s disease. Super thankful to <a href="/BlurtonJonesLab/">Blurton-Jones Lab</a> and the entire MBJ team for their continuous support!
Jean Paul Chadarevian (@jpchadarevian) 's Twitter Profile Photo

We are excited to share our newest publication from the Blurton-Jones Lab, "Harnessing human iPSC-moceoglia for CNS-wide delivery of disease modifying proteins." sciencedirect.com/science/articl…

We are excited to share our newest publication from the <a href="/BlurtonJonesLab/">Blurton-Jones Lab</a>, "Harnessing human iPSC-moceoglia for CNS-wide delivery of disease modifying proteins."
sciencedirect.com/science/articl…
Ghazaleh Eskandari-Sedighi (@ghazalehesk) 's Twitter Profile Photo

Congratulations to Jean Paul Chadarevian and the whole Blurton-Jones team for this beautiful piece of work: Harnessing human iPSC-microglia for CNS-wide delivery of disease modifying proteins." 👍👍👍

Peng Jiang Lab (@labjiang) 's Twitter Profile Photo

“Chimeric models of breast cancer brain metastases and demyelination” — such an interesting and innovative approach! Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins: Cell Stem Cell cell.com/cell-stem-cell…