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It's out! We found that the railroad network (microtubule array) in neurites is extremely dynamic during development and moves retrogradely into the soma. New data compared to preprint - dynein, actin and much more. Get ready for lots of movies!🧵👇 science.org/doi/10.1126/sc… (1/25)

so true 🎯!! thanks for your perseverance with preprints Christophe Leterrier

How can the weak survive in this competitive world? This beautiful movie shows the fierce competition between actin networks for scarce resources. A central rule of biological ecosystems captured by a minimal reconstituted system. Congratulations to Guerin and Alexandra Colin !

We have a new preprint out! It's about the molecularly diverse world of Intracellular Nanovesicles (INVs). ATG9 vesicles are a subtype of intracellular nanovesicle biorxiv.org/content/10.110… Mary Fesenko @Moore_cell Peyton Ewbank in Royle Lab News mechanochemistry 1/n

Our new paper, in collaboration with the Karolina Skvarova group Univerzita Karlova Fakultní nemocnice v Motole, reveals that patients with the c.269 T>C variant in AP1S1 manifest all symptoms of MEDNIK syndrome, not just enteropathy. 📄 Read it here: rdcu.be/dTW2o.

The English version is out. Spread it and display it in your labs!

We have an open postdoc position in the NeuroCyto lab! Come explore new mechanisms of microtubule turnover and their physiological roles in collaboration with THERY Manuel, funded by ANR for up to 3 years. More info & contact: neurocytolab.org/postdoc/ Thanks for RTs🙏🏻

Marseille, microtubules, microscopy. What else?

Yes, yes, Friday! #Myotwitter #FluorescenceFriday

Happy #FluorescenceFriday for those who celebrate. There is only one cytoskeleton #trinity

It’s finally out! Time resolved proximity proteomics of caveolae in response to membrane tension! Thank you eLife and all reviewers for the fair review. We tried hard to add more beef to the second part of the story but simply got stuck. Check it out elifesciences.org/articles/85601

Denis Furling devient le nouveau directeur du centre de recherche en myologie : ow.ly/vQ7n50TunxB

🧬Our latest research is now online on medRxiv!🧬 We show that heterozygous variants in SPTAN1 cause a novel type of distal myopathy. While α-2-spectrin is well-known for its role in the axonal membrane periodic system, its function in muscle fibers is less explored🤔

Transferrin receptor targeting chimeras for membrane protein degradation nature.com/articles/s4158…

Active cellular water pump for osmoregulation. Unicellular organisms in fresh water need to actively pump water out to balance the large flux of water coming in due to osmotic pressure difference. No molecular water pumps are known, so this water pump must be supramolecular.

Ivaska Lab THE review on 'everything' you have ever wanted to know about integrins in cancer, invasion and migration. Many cool new concepts highlighted from the beautiful research from experts in the field 👇Megan Chastney #VMLeppänen #JasminKaivola rdcu.be/dVB6n

With help from Roux Lab, Marko Kaksonen, Wanda Kukulski Steph Vassilopoulos, we dived into the world of mysterious bi-layered clathrin coats on endosomes. I’m very excited to share this work and looking forward to hearing your thoughts! biorxiv.org/content/10.110…

the role of protein condensates in sorting cargoes and flattening membranes in the ESCRT-0 complex. Amazing work from Markku, a fantastic collaboration with Marko Kaksonen Wanda Kukulski Steph Vassilopoulos, thank you all!

So happy to finally see this out! Great work by first authors Alexander Stockhammer and Petia Adarska which have shown that cargo flow along post-Golgi routes is driven by a key maturation step where compartments defined by ARF1 nature into recycling endosomes nature.com/articles/s4155…

Excited to see our latest study published in nature. We report several structures of the intriguing LYCHOS (GPR155) protein revealing a chimeric structure of a GPCR and a PIN-like transporter domain. nature.com/articles/s4158…