It is clear. If there is one thing we owe to patients, hemato-oncologists, pathologists, clinical trialists, scientists & regulators is to unify the CAC/ICC & WHO classification ASAP. Why wait for the next revision? #ASH22 inspiration

Very interesting data suggesting that the addition of lenalidomide to R-CHOP (R2CHOP) improves OS and PFS in MYC-R DLBCL Can’t wait to read the paper 📝 #lymphoma #ASH22

Régis Peffault de Latour presents the very successful iptacopan (proximal complement inhibitor) in #PNH #LBA at #ASH22 Primary endpoints met with excellent control of intravascular and extravascular haemolytic. Congratulations my friend.

Hey #medicine residents !! 𝐍𝐎𝐓 𝐀𝐋𝐋 𝐇𝐄𝐌𝐎𝐋𝐘𝐓𝐈𝐂 𝐀𝐍𝐄𝐌𝐈𝐀 𝐰/ 𝐚 𝐏𝐎𝐒𝐈𝐓𝐈𝐕𝐄 𝐂𝐎𝐎𝐌𝐁'𝐒 𝐓𝐄𝐒𝐓 𝐢𝐬 𝐀𝐈𝐇𝐀 ! 𝐅𝐀𝐋𝐒𝐄 + 𝐂𝐨𝐨𝐦𝐛'𝐬 𝐭𝐞𝐬𝐭: 🔸Post blood transfusion 🔸Post IVIG 🔸HCV/HIV/rarely HBV 🔸Antiphospholipid syndrome #MedTwitter

1/2 See graphic for CBC result, put on your thinking cap and answer the following questions🤔: 1. What skin symptom might the patient complain of? 2. Why does the patient have a ruddy complexion? 3. Is this patient or one with anemia more likely to develop cyanosis?

As 2022 wraps up, it is time for a🧵 that highlights 10 pivotal trials that informed my practice and thinking in 2022. These are articles published in 2022 (although initial results/online pub maybe earlier)- abstracts from meetings covered elsewhere. Myeloma 2022 Recap 👇 #mmsm

An antibody for myelofibrosis – “that’s a true discovery” - Leukaemia Foundation leukaemia.org.au/stories/an-ant…

1/9 Hematologists are comfortable diagnosing and treating Fe deficiency. However, many of us are outside our comfort zone when it comes to chronic kidney disease. Why? Because the diagnostic criteria and indications for treatment are so vastly different, even antithetical.

A timely and important study on patient perspective about #CHIP. While most patients were interested in testing, it also produced significant anxiety. A nuanced, case by case approach with a lot of counseling is needed. #mdssm #amlsm (1) ashpublications.org/bloodadvances/…

Food for thought: The hematocrit (Hct) is IMPERVIOUS to the hemoglobin (Hb). The ONLY determinants of Hct are RBC count and MCV. So, it is theoretically possible to have a normal Hct with Hb 0.0. ***Only Hb is a marker of oxygen carrying capacity of blood***

1/ Excited to share our study with Olli Dufva suggesting venetoclax resistance and BCL-XL dependence in erythroid/megakaryoblastic AML @BloodJournal doi.org/10.1182/blood.…

Patient with WM has 180k WBC but they are missing in the blood film! Repeat testing shows similar findings. Where are they!? What’s going on!? #Lymsm #Blooducation Xitlaly Gonzalez

🚨Interacciones farmacológicas habituales en la unidades intensivos 🏥🤨 Todo lo que NO se puede escapar!⬇️ #Mejorandolaatenciondelpaciente sefh.es/fh/221_13180_1…

At ASH #ASH22 highlights I am being told some transplanters are refusing to do #AlloHSCT for otherwise eligible #AMLSm younger pts in CR because of bialleic #TP53 +MRD, I don’t think this is acceptable. Counsel on poor outcomes but there is a tail at end of OS curve

Happy New Year and welcome to the first #EHAcase morphology challenge of 2023. Please take a look at the image below and answer the question given. Stay tuned and we will return later today with the correct answer. See you later!

Ponatinib + Hyper-CVAD in Ph+ ALL = 6-yr OS 75%; no need for SCT if CMR. Another good standard of care. MD Anderson Cancer Center #Leukemia doi.org/10.1002/ajh.26… via AmericanJournalofHematology #leusm #ALL

Achieving MRD negativity in #AML: how important is this and how do we get there? ashpublications.org/hematology/art…

Hola, el CATB-NHPG es un grupo multidisciplinar para el estudio de Neoplasias Hematológicas de predisposición germinal. Puedes seguirnos en twitter si quieres saber más sobre nosotros ¡Te invitamos a participar en nuestro 1er QUIZ¡ #SEHH #SCHH #hematology

icMDS presents the most recent important publication on MDS preclinical and translational research. A brief guide: 1. Preclinical models of MDS based on the pathogenesis 2. MDS genetic aspects - molecular defined MDS - germline predisposition - CHIP and CCUS--> MDS

We are glad to share our new work regarding NETosis in vitro on plasma samples from patients undergoing AlloHSCT. Hematologia HUSE . Plasma can induce NETosis in vitro on donor neutrophils. Thanks to all the authors and patients who donated samples. frontiersin.org/journals/immun…