Thomas Bajaj
@bajajthomas
Neuroscientist interested in autophagy, lysosome biology, organelle homeostasis and molecular biology of glucocorticoid signaling @UniklinikBonn
ID: 1251409274183593985
https://de.linkedin.com/in/thomas-bajaj-262284ba 18-04-2020 07:16:49
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461 Following
Very excited to share the recent work from our lab just published in Science Advances science.org/doi/full/10.11… True team effort with the fabulous Nils Gassen spearheaded by two rising stars in stress and metabolism research Alexander Häusl and Thomas Bajaj Here is what we found 1/n
Check out our MBH-FKBP51 Punctum in Autophagy on Alexander Häusl’s and #BajajThomas’ Paper from the Mathias Schmidt and Nils Gassen labs that got recently published in Science Advances! tandfonline.com/doi/full/10.10…
Thank You Nature Communications for featuring our research on CoV-2-mediated dysregulation of metabolism and autophagy among the most impactful and innovative articles in your COVID-19 collection: nature.com/collections/ac… Check it out! nature.com/articles/s4146… Nils Gassen and Marcel A. Muller
Long-term collaborator Nils Gassen from #UKBonn will join #ChariteVirology as guest prof to study with me the differential stress response and inflammation during virus infections in bats vs. human cells. Thanks Stiftung Charité Charité - Universitätsmedizin Berlin Christian Drosten x.com/StiftungCharit…
Truly stimulating work from the Nils Gassen lab just out in Cell Reports! 🫘🧠⚡️🦛 >💡🐭 🆙 Uncoupling KIBRA/WWC1 from the Hippo pathway to AMPAR-reg. complexes promotes long-term memory formation. Wonderful study and graphical abstract by Matteo Oliverio cell.com/cell-reports/f…
Interested in mechanisms of neuroinflammation? Check out our preprint demonstrating that SKA2 and FKBP5 impact neuroinflammation via regulation of secretory autophagy. Huge team effort with Nils Gassen and Kerry Ressler SPARED Center at McLean Hospital and many more! biorxiv.org/content/10.110…
Check out this impressive new paper by Jakob Hartmann and colleagues, uncovering a new mechanism how the psychiatric risk factors Ska2 and FKBP5 impact secretory autophagy and neuroinflammation. Huge implications for psychiatric disorders. Happy we could contribute.
🧬💡Excited to share our work McLean Hospital SPARED Center at McLean Hospital Harvard Medical School Broad Institute on cell-type-specific molecular underpinnings of #PTSD Journals of The American Psychiatric Association #AJP ! It represents the 1st #singlecell study of dorsolateral prefrontal cortex #PFC in PTSD! doi.org/10.1176/appi.a… 1/x
Great new paper from the Jakob Hartmann and Nils Gassen labs, to which we were lucky to contribute. We identify a mechanism by which #SKA2 regulates #autophagy & contributes to neuroinflammation-induced neurodegeneration. Link to #Alzheimer's disease! nature.com/articles/s4146…
So happy to finally see our study on novel regulators of secretory autophagy and their impact on neuroinflammation published in Nature Communications 🧠🔥🔬 Incredibly thankful to all my co-authors for their contributions! nature.com/articles/s4146…
Great retreat supported by Stiftung Charité with the team of guest prof Nils Gassen from @UKBonn and my team from Charité - Universitätsmedizin Berlin trailblazing research on #stress & #infection
Memory Breakthrough from the Nils Gassen Lab: Disrupting Hippo Kinases to Supercharge Synaptic Plasticity and Memory in Mice! 🧠 Check it out 👇🏼 science.org/doi/10.1126/sc…
Inhibitors of the kinases MST1/2 in #HippoSignaling boost memory in aged mice and models of #AlzheimersDisease by promoting the incorporation of the scaffolding protein WWC1 into AMPAR complexes, show new experiments from Nils Gassen lab. Max Planck Institute of Psychiatry scim.ag/6Pz
Check out our SKA2 Punctum in Autophagy on our fascinating paper about SKA2-regulated Secretory Autophagy from the Jakob Hartmann and Nils Gassen labs, recently published in Nature Communications! 🧠🔥 👇tandfonline.com/doi/full/10.10… + nature.com/articles/s4146…
🥂Thrilled to see my latest #postdoc work out! What began as a quick, fun side project just before the first lockdown led me down a rabbit hole and ended in Nature Cell Biology 4.5y later: nature.com/articles/s4155… #autophagy #polyamines #fasting #caloricrestriction🧵1/11
💫NEW: Sebastian J. Hofer et al. show that fasting promotes the synthesis of #spermidine, which stimulates eIF5A hypusination to induce #autophagy and increase #lifespan in various species in a conserved manner. Uni Graz/University of Graz nature.com/articles/s4155…
We've uncovered sex-specific effects of early-life stress (ELS) exposure on fear memory, HPA-axis regulation, and brain metabolism🧠. Unsupervised clustering shows that fear responses are more than only freezing Communications Biology nature.com/articles/s4200… Highlights in thread👇