Super excited to announce that Mike Mitchell MD PhD student Rohan Palanki roro 's thesis defense titled "Ionizable lipid nanoparticles for in utero gene editing of congenital disease" is this Wednesday at 1PM! Link to location and Zoom: bit.ly/49jPUS5

Super excited to share our latest in Journal of Controlled Release J Controlled Release led by Mike Mitchell PhD student Hannah Geisler Hannah Geisler on antibody-conjugated LNP tech for targeted RNA delivery to the placenta! Link: sciencedirect.com/science/articl…

Check out our latest in ACS Nano ACS Nano led by Mike Mitchell PhD student Alex Hamilton Alex Hamilton on high-throughput in vivo screening to identify LNPs tailored for local and systemic delivery for mRNA vaccines + cancer immunotherapy applications! Link: pubs.acs.org/doi/full/10.10…

Could *Notch* have had a better time at my first Gordon Research Conferences! Thanks to past & future GRS chairs Ishita Jain Thilinie Bandara Ajay Thatte & Marlene for fostering such a fun & supportive community. Grateful to be heading home (amidst the travel chaos) with new ideas & new friends. ❤️

Had a wonderful time presenting my first conference talk at the Notch GRS/GRC Gordon Research Conferences! Excited to now be part of such a scientifically vibrant and close-knit community. Looking forward to organizing the next meeting with Marlene Assfalg, Emma Andersson and Wendy Gordon lab UMN!

Thankful to @NICHD_NIH for awarding us a new R01 grant on our mRNA lipid nanoparticle pregnancy research led by Kelsey Swingle Hannah Safford Hannah Geisler! We are recruiting postdocs and PhD students in women's health and nanotech, contact us via email or at #BMES2024!

Excited to contribute to this special issue highlighting drug delivery strategies for next-gen autoimmunity therapies!

Thrilled to share our full special issue on drug delivery tech for autoimmunity therapies in Editors of Advanced Drug Delivery Reviews co-edited with Weaver Lab Ryan M. Pearson, PhD Adam Gormley! Issue: sciencedirect.com/special-issue/… Editorial led by Ajay Thatte: sciencedirect.com/science/articl… Amazing contributions including:

Emerging strategies for nanomedicine in autoimmunity by Ajay Thatte Maggie Billingsley, PhD Jilian Melamed The Drew Weissman Lab Mike Mitchell Link: sciencedirect.com/science/articl…

Enjoyed highlighting this comprehensive study in Nature Chemical Engineering linking biophysical cues to mechanisms of gene delivery!

Come check out a killer poster by Hannah Yamagata on a new class of aromatic lipid nanoparticles that outperform industry standard mRNA vaccines this morning at 10am at #BMES2024! We also have two posters by Mike Mitchell undergrads Ben Nachod and Sridatta Teerdhala!

Thrilled to share our recent work out today in nature on an mRNA therapeutic to treat pre-eclampsia! This work has been a true passion project from my time Penn Bioengineering in Mike Mitchell, and I’m excited to continue important research in women’s health! nature.com/articles/s4158…

Very excited to share our new work, now on bioRxiv, on specificity of memory in human macrophages biorxiv.org/content/10.110… (1/8)

Standing room only for Kelsey Swingle’s seminar on mRNA LNPs to treat pregnancy disorders at Penn’s Center for Women’s Health hosted by Dr. Marisa Bartolomei! What a special opportunity to see one of our own from Mike Mitchell give their faculty interview seminar on campus! #proudPI

Congrats to star undergrad, Ben Nachod for winning the William C. Hall Scholarship! Great job! 🎉Mike Mitchell Penn Engineering Penn Bioengineering

Check out our latest publication in @nanoletters led by Mike Mitchell PhD student and lab softball Coach Hannah Safford where we explore tuning LNP elasticity using atomic force microscopy to enhance mRNA LNP delivery to the placenta! Link to article: pubs.acs.org/doi/full/10.10…

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j3xGs8

Mitchell Lab is off to #CRS2025 to give 8 talks by Junchao Xu Emily Han Dongyoon Kim Hannah Geisler Qiangqiang Shi Hannah Yamagata Hannah Safford on mRNA vaccines, lipid nanoparticles, cancer immunotherapy, fetal and maternal health, CNS targeting and more! Controlled Release Society

We will also have two posters by Ajay Thatte on steroid lipid nanoparticles for mRNA autoimmune disease therapeutics and Melgious Ang on photoactivatable lipid nanoparticles! #CRS2025 Controlled Release Society

Thank you to #CRS2025 for the award! Huge thanks to Mike Mitchell for all the support and The Drew Weissman Lab Jilian Melamed for being the best collaborators!