Link to Nano Letters article: pubs.acs.org/doi/10.1021/ac…

Check out our latest in Theranostics Theranostics led by former Mike Mitchell undergrad Savan Patel Savan Patel on a new bile acid lipid nanoparticle platform to enhance mRNA delivery beyond the liver! Free access: thno.org/v14p0001.htm

Huge congrats to Mike Mitchell PhD student Ajay Thatte Ajay Thatte for being featured on the cover of Nano Letters for his new mRNA lipid nanoparticle tech to engineer T cells to treat autoimmune diseases! Issue link: pubs.acs.org/toc/nalefd/23/… Article link: pubs.acs.org/doi/10.1021/ac…

So excited to have my final first author paper from my PhD in Mike Mitchell at Penn Bioengineering come out this weekend in Small! Using antibody functionalized lipid nanoparticles, we demonstrate in vivo T cell transfection for CAR T cell engineering 🧫 🧬 onlinelibrary.wiley.com/doi/10.1002/sm…

Thrilled to announce that my first review on responsive biomaterials for cancer immunotherapy is now out in NatRevMaterials! Special shoutout to my partner-in-crime Lulu Xue, Ph.D for being the best co-author and to the entire Mike Mitchell team for their support!

Wonderful review by Mike Mitchell Carl June, Karin Wang and associates on "Responsive Biomaterials: Optimizing Control of Cancer Immunotherapy" in Nature Reviews Materials scholar.google.com/scholar_url?ur…

Congratulations to Sonja Schrepfer and the team at Sana for curing a nonhuman primate with allogeneic islets without requiring immunosuppression! cell.com/cell-stem-cell…

Excited to share my review article on nanomedicine in autoimmunity, now out in ADDR! Thank you to Maggie Billingsley, PhD Jilian Melamed The Drew Weissman Lab and Mike Mitchell for being the best support system! Looking forward to exploring this area further 🔬

Check out our latest in Advanced Functional Materials Advanced Sci News led by Mike Mitchell PhD student Alvin Mukalel Alvin Mukalel on new oxidized mRNA lipid nanoparticle tech for making CAR monocytes in the body for cancer immunotherapy! Free access: onlinelibrary.wiley.com/doi/10.1002/ad…

Check out our latest in Advanced Materials Advanced Sci News led by Mike Mitchell PhD student Ann Metzloff on antigen presenting cell-mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy! Free access: onlinelibrary.wiley.com/doi/10.1002/ad… Penn story: blog.seas.upenn.edu/accelerating-c…

Super excited to announce that Mike Mitchell MD PhD student Rohan Palanki roro, phd 's thesis defense titled "Ionizable lipid nanoparticles for in utero gene editing of congenital disease" is this Wednesday at 1PM! Link to location and Zoom: bit.ly/49jPUS5

Super excited to share our latest in Journal of Controlled Release J Controlled Release led by Mike Mitchell PhD student Hannah Geisler Hannah Geisler on antibody-conjugated LNP tech for targeted RNA delivery to the placenta! Link: sciencedirect.com/science/articl…

Check out our latest in ACS Nano ACS Nano led by Mike Mitchell PhD student Alex Hamilton Alex Hamilton on high-throughput in vivo screening to identify LNPs tailored for local and systemic delivery for mRNA vaccines + cancer immunotherapy applications! Link: pubs.acs.org/doi/full/10.10…

Could *Notch* have had a better time at my first Gordon Research Conferences! Thanks to past & future GRS chairs Ishita Jain Thilinie Bandara Ajay Thatte & Marlene for fostering such a fun & supportive community. Grateful to be heading home (amidst the travel chaos) with new ideas & new friends. ❤️

Had a wonderful time presenting my first conference talk at the Notch GRS/GRC Gordon Research Conferences! Excited to now be part of such a scientifically vibrant and close-knit community. Looking forward to organizing the next meeting with Marlene Assfalg, Emma Andersson and Wendy Gordon lab UMN!

Thankful to NICHD News for awarding us a new R01 grant on our mRNA lipid nanoparticle pregnancy research led by Kelsey Swingle Hannah Safford Hannah Geisler! We are recruiting postdocs and PhD students in women's health and nanotech, contact us via email or at #BMES2024!

Excited to contribute to this special issue highlighting drug delivery strategies for next-gen autoimmunity therapies!

Thrilled to share our full special issue on drug delivery tech for autoimmunity therapies in Editors of Advanced Drug Delivery Reviews co-edited with Weaver Lab Ryan M. Pearson, PhD Adam Gormley! Issue: sciencedirect.com/special-issue/… Editorial led by Ajay Thatte: sciencedirect.com/science/articl… Amazing contributions including:

Emerging strategies for nanomedicine in autoimmunity by Ajay Thatte Maggie Billingsley, PhD Jilian Melamed The Drew Weissman Lab Mike Mitchell Link: sciencedirect.com/science/articl…

Enjoyed highlighting this comprehensive study in Nature Chemical Engineering linking biophysical cues to mechanisms of gene delivery!