Noa Argamani (25), Almog Meir Jan (21), Andrey Kozlov (27), and Shlomi Ziv (40) were rescued in a special operation by the IDF, ISA and Israel Police from 2 separate locations in the heart of Nuseirat after being kidnapped by Hamas from the Nova music festival. They are in good

If you ever wondered about the identity of the colabfold/foldseek mascots, you are not the only one! Many thanks to Martin Steinegger 🇺🇦 for providing explanations at the #EMBOmacromolecular course in Grenoble!

Going viral: The role of mobile genetic elements in bacterial immunity Beatriz Beamud fabienne.benz David Bikard review work revealing that most bacterial defense systems are carried by mobile elements, indicating complex evolutionary forces driving immunity cell.com/cell-host-micr…

Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection •Host membrane & proteins are rapidly recruited during phage ΦKZ infection •Vesicle protects the injected genome from nucleases prior to #phage nucleus assembly cell.com/cell-host-micr…

Interested in uncovering the molecular workings of new antiphage defences? We are looking to fill two 3-year postdoctoral positions via Marie Skłodowska-Curie scheme AMBER. Please read carefully and contact me so we can polish your idea! RT appreciated! lu.varbi.com/en/what:job/jo…

It has been public for a while, but with #VoM2024 starting, today is as good as any to introduce our new tool phage genome annotation tool Phold. Phold uses structural homology to assign functions to phage proteins (1/n)

A bacterial TIR-based immune system senses viral capsids to initiate defense biorxiv.org/content/10.110… 2/2

The prisoners released by Russia included U.S. and German citizens, but many of them were Russian citizens jailed for opposing the Putin regime or the war in Ukraine. Here are some of the first reactions from the loved ones of these now-exiled Russians. meduza.io/en/feature/202…

FoldMason progressively aligns thousands of protein structures in seconds, enabling remote MSA for distant phylogeny. Highlights: structural flexible MSA, LDDT conservation score, friendly webserver🧵 💾github.com/steineggerlab/… 🌐search.foldseek.com/foldmason 📄biorxiv.org/content/10.110…

Thanks to all of you joined, raised questions and made this afternoon very enjoyable!! Hope we soon be able to this again.

Foldmason, our fast and accurate protein structure-base multiple sequence alignment method, has a logo thanks to HBKgenomics. Also, we updated the preprint, including a multi-domain protein benchmark. 📄biorxiv.org/content/10.110… 💾foldmason.steineggerlab.com 🌐search.foldseek.com/foldmason

Our collaboration with WilsonLab and Vicent Pelechano is out in Nucleic Acids Res! The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site academic.oup.com/nar/advance-ar…

Please give it a go - and give feedback! And stay tuned for more awesome stuff from Artyom Egorov and Gemma C Atkinson !

In a new study, we report the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of mammalian innate immunity!! Co-led with Enzo Poirier lab, in collab with Ben Morehouse biorxiv.org/content/10.110…

LoVis4u v0.0.9 is released. Now with new compact styles for A4 layouts, including one- and two-column figures with adjusted fonts and object sizes. Check out the examples in the gallery and visit the new user guide page: art-egorov.github.io/lovis4u/Galler…

Am Yisrael Chai 🇮🇱

Glad to see this beast out in the wild, incredible collab. with Carl de Boer's lab on modeling promoter sequences with advanced DNNs. Congratulations to the team incl. Dmitry Penzar Daria Nogina Arsenii Zinkevich. Spoiler: expect more wonders from Dmitry's LegNet later this year.

See our preprint on systematic hotspot annotation! In addition to hotspot analysis, we provide precomputed iLund4u databases and two search modes: find if your query proteins are encoded in hotspots or map hotspots to a single phage/plasmid sequence. biorxiv.org/content/10.110…

New version of LoVis4u is released! 💛 Now it supports visualisation of non-coding features like tRNAs and includes a new module for hmmscan searches against DefenseFinder, PADLOC, VFDB, AMRFinder, dbAPIS (anti-defences), or your own databases. Homepage: art-egorov.github.io/lovis4u

Minus one in the set of iLund4u discovered systems for our lab… hope others will survive in this hot environment 🥲 🔥 Congrats to colleagues!