This is effectively a cure for type 1 diabetes. Autologous, (chemically) reprogrammed iPSCs were engineered from a patient's fat cells and injected back into her stomach. After ~2.5 months, she no longer needed insulin and now enjoys ice cream + candy like a normal person.

As promised, a 🧵 on our recent article now out in NatureStructMolBiol! Co-led with Abby Bartlett Pagliarini Lab Judith Simcox PhD, we find ACAD10/11 are NOT like other acyl-CoA dehydrogenases and instead catabolize atypical lipids called 4-hydroxy acids 🤯#lipidtime doi.org/10.1038/s41594…

Guess we’re gonna have to ask our favorite AI chatbots to predict drug efficacy instead of doing preclinical studies now

Excited to share our study out in Circulation identifying the ability of PHF7 to activate cellular reprogramming and recover function in the heart following myocardial infarction. Grateful to Eric N. Olson and the great team who made this work possible! ahajournals.org/doi/10.1161/CI…

Excited to receive an NIH K08 Clinical Investigator Award to support my research on #mitochondria #peroxisomes 😀 The $775K will be critical in helping me transition to independence as I begin looking for a place to start my lab 🙏🏻 APSA ASCI American Academy of Pediatrics #neotwitter

So excited to see this amazing work published from an amazing friend and colleague. It's amazing to see that PHF7 alone has such an effect on restoring cardiac function after MI. Congrats Glynnis Garry Bann

While I’m a big fan of new technologies that help us study human biology…there’s still no replacement for animal research! I wrote an article outlining this in Genetic Engineering & Biotechnology News genengnews.com/topics/transla…

Losing your mentor is a painful experience. When asked “what do you consider to be your greatest achievement? Dr. Ken Storey always said “My students!” Thank you for the countless lessons in science and life, the jokes, and the music! ⁦⁦⁦⁦⁦Carleton Science⁩

Muscle mass predicts lifespan better than BMI or weight - so get moving and get lifting

This has to be the best? or worst poster I've ever seen 😂

It’s with deep regret that I share the passing of my master of science mentor, Dr. Kenneth B. Storey. Ken was a renowned scientist from Carleton university. More than that, he was a man who inspired me to pursue a career in science. For that I’m forever grateful. Goodbye Ken

🔬🧪🧬Thanks to the Agencia Estatal de Investigación for funding my project #CardioDNA, aimed at studying genetic diseases that affect the heart. ✅🏛️This institutional support will allow me to open my own lab on September 1st at the IBBTEC Universidad de Cantabria

I spent 1.5 years at MIT designing a new undergraduate program in Genetic Engineering. One of our theses in designing that program (which I’ll share more about soon; I'm writing a long essay about it) was that undergraduate students could be trained to be excellent genetic

A simple benchmark. Most people can understand it. No PhD-level intelligence needed.

We’re deeply saddened by the passing of David “Davo” Mangelsdorf, Ph.D., Professor and Chair of Pharmacology at UTSW, whose work on orphan nuclear receptors transformed our understanding of metabolism and endocrinology and inspired countless scientists. bit.ly/47jN4hK

Everyone needs to hear this…

What is the endgame for ANGPTL3? $LLY in their website update just added VERVE-201 alongside the PCSK9 editor VERVE-102 in their list of phase 1 programs. With ANGPTL3 the siRNA results ($LLY, $ARWR) have been quite different from the ASO data (Ionis). It'll be intriguing to

I’d say most PhD students don’t even have ONE of these !

Can’t wait to see the transactivators again next month for the Myo-life symposium!