Urea, also known as *carbamide*, is a safe, useful compound with a significant history. It is a naturally occurring molecule that is produced by protein metabolism and found abundantly in mammalian urine.
Contraindications for conserving a catheter in CRBSI
📍Hemodynamic instability
📍Exit site infection
📍Metastatic foci (IE, OM etc.)
📍Prosthesis in situ
📍Staph aureus/Candida on cultures (Difficult to eradicate bugs).
[1/26, 10:44 PM] sandeep paryani: Even lose methotrexate (5-15 mg/week) should not be prescribed in dialysis patients with rheumatoid arthritis ❌
👹Can lead to profound myelosuppression.
DMARD of choice in RA 🦴
Methotrexate & renal correction 🫘
🔷 CrCl >50 mL/minute: No dose adjustment necessary.
🔷 CrCl 10 to 50 mL/minute: Administer 50% of dose.
♦️ CrCl <10 mL/minute: Avoid use