Our Guide to Performing Polygenic Risk Score analyses out now in Nature Protocols - hope this is useful for those working on polygenic risk! Fantastic work by Choi Shing Wan on this and the online tutorial that guides users through PRS analysis with code/data! nature.com/articles/s4159…

Thanks BlackInGenetics & your topic yesterday was really important because too few people know that: 1. Labels of ‘race’ don’t match to genetics well at all! (about as informative as a book-cover is to a book) 2. African genetics are the most diverse! (ie. most interesting)

Fantastic PhD work by new lab member @Juditperala who just joined us as a postdoc in the SklarPsychGen at Sinai in NYC!! Welcome to New York City and Mount Sinai Judit!!

A great opportunity to work with a fantastic supervisor in a friendly, brilliant and productive team. Science twitter, please retweet...Science Grrl The Genetics Society Paul O'Reilly Inga Prokopenko @AndrewJWalley @JessGenetics Robin Walters

New preprint out! "High-resolution portability of 240 polygenic scores when derived and applied in the same cohort" doi.org/10.1101/2021.0… cc Bjarni Vilhjalmsson lassefolkersen Paul O'Reilly and H. Aschard and C. Hoggart 1/n

Our nature News&Views article is out today x.com/Nature/status/… It was great fun to work on this with Paul O'Reilly!! 1/4

We’re hiring!! Postdoc ($70k-$80k) and Asst Prof ($110k) positions available in our lab in New York!! Seeking candidates with strong stat/comp backgrounds, passionate about developing methods/software in Stat Gen, Pop Gen, Gen Epi. Job advert here: tinyurl.com/2p95v899 PLS RT!

Applications for the Seaver Undergraduate Research Scholars program opens NOW! PAID studentships for NYC-based undergraduate students from under-represented backgrounds to work on #autism research with Seaver Autism Center faculty! tinyurl.com/ysnyb9rb for details/application

Our #Pathway #PRS paper out now in PLOS Genetics!!! Amazing work by @Juditperala Choi Shing Wan Yunfeng Ruan🌻 #StandWithUkraine🌻 on this + many others. DM/email us with any thoughts or questions as we want the #PRSet (/#PRSice) software to be useful for people!!

Our new paper on using siblings to infer genetic architecture!! Tade Souaiaia presenting on this at poster #S20 at #ICHG2023 today (nice work Tade!! + Clive/Beatrice). Feeling very lucky to be in beautiful Cape Town for #ICHG2023!! biorxiv.org/content/10.110…

Fantastic work (& poster 🎯💫) Anil!! Those at #ICHG2023 do stop by Anil’s poster!! (a great discussion guaranteed!)

Fantastic work by Clive Hoggart on development of our BridgePRS method for improving PRS prediction across ancestries - just out in Nature Genetics! (thanks to Choi Shing Wan @Juditperala Tade Souaiaia Michael_Preuss too 👌) nature.com/articles/s4158…

Polygenic Score Workshop this summer in Japan that we’re running with Yuki Okada and team - for details and registration -> sg.med.osaka-u.ac.jp/school_2024.ht…

Last chance to register for our PRS Workshop in Tokyo!! See details here -> sg.med.osaka-u.ac.jp/school_2024.ht… Please RT 🙏

Thanks so much for hosting the PRS Workshop in Tokyo YukinoriOkada (+ special thanks to Norie!) - amazing hosts, setting and participants!! 👌🇯🇵

Fantastic work from incredible scientist Anil Ori - looking forward to more collab on this Anil!! For anyone wanting to know more abt this topic at #ASHG24 then come along to poster 4051T that I’m presenting from 2:30pm today - it'll be great to get your Qs & feedback on this!

Interested in pathway enrichment? Go see @AlannaCote2’s poster 6059F from 2:30pm at #ASHG24!! Our lab was extremely lucky to have Alanna join as a postdoc this year - making important advances on pathway enrichment already!! 💫 (go to 6059F to ask Alanna more about that)