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Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis cancerres.aacrjournals.org/content/early/…

Our NEW Review by Chris Iacobuzio @sloan_kettering & colleagues discusses the rationale for using research autopsies in cancer research - this approach has improved knowledge of cancer biology & could inform precision medicine strategies. Cancer at Nature Portfolio go.nature.com/2kjJ1gp

Our paper on the identification of cancer-restraining fibroblasts in PDAC appeared in current issue of Cancer Research🍻 We thank Daniel Worthley and Susi at SAHMRI and the Wisconsin team for inspiring us😆 Great work by Mizutani san, Kobayashi kun, Iida san👏 cancerres.aacrjournals.org/content/79/20/…

#Cancer-associated fibroblasts are critical components of the tumour mesenchyme. In this REVIEW, the authors outline the emerging understanding of #gastrointestinal cancer-associated fibroblasts go.nature.com/2SieWZB

SAHMRI researchers are finding new avenues to attack bowel cancers that don’t respond to initial treatments 🎗 Dr Susan Woods (SAHMRI / Uni of Adelaide) co-led the project, a multisite collaboration involving Peter Mac Research and supported by Cancer Council SA sahmri.org/precision-medi…

Medium-throughput drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy clincancerres.aacrjournals.org/content/early/…

Drug screening of patient-derived organoids from colorectal peritoneal metastases to direct personalized therapy clincancerres.aacrjournals.org/content/early/… Cancer Council SA SAHMRI Peter Mac Cancer Centre SEngine Precision Medicine Siddhartha Mukherjee

How #bowelcancer corrupts accomplice cells #CAFs, what those cells produce #BMP & how BMP-signalling may be targeted by viral therapy to improve survival. Well done Hiroki Kobayashi⁩ ⁦Atsushi Enomoto SusiWoods⁩ SAHMRI⁩ ⁦⁦Gastroenterology⁩ gastrojournal.org/article/S0016-…

New gene therapy could help liver metastasis. Awesome int’l collaboration! 🇦🇺🇯🇵🇬🇧🇺🇸 9news.com.au/national/adela… Jodi Lee Foundation SAHMRI Cancer Council SA Hiroki Kobayashi Atsushi Enomoto

Congratulations Hiroki Kobayashi!Thank you Atsushi Enomoto! Hiroki has been such a joy to work with and he has plenty more still to come.

The origin and contribution of cancer-associated fibroblasts in colorectal carcinogenesis gastrojournal.org/article/S0016-… ⁦Daniel Worthley⁩

Delighted to share our work out today in Cell Reports Medicine. The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota cell.com/cell-reports-m… Flinders University SAHMRI EMBL Australia NHMRC Tour De Cure

New content online: Origin of CAFs in colorectal cancer dlvr.it/SGXD06

Our study on the origin and contribution of colorectal cancer associated fibroblasts is on the cover of the March issue of Gastroenterology for #nationalcolorectalcancerawarenessmonth. Thank you to Gastroenterology & the whole team Hiroki Kobayashi Susi Woods colonoscopyclinic SAHMRI

Now online in Cancer Discovery: Neuro-Mesenchymal Interaction Mediated by a β2 Adrenergic-Nerve Growth Factor Feedforward Loop Promotes #ColorectalCancer Progression - by Hiroki Kobayashi, Timothy Wang & colleagues doi.org/10.1158/2159-8… Columbia Medicine Herbert Irving Comprehensive Cancer Center #CancerNeuroscience