Does the evolutionary history of a cancer predict outcome? In our pre-print, we introduce a new method to measure a cancer’s past using bulk methylation data. In chronic lymphocytic leukaemia (CLL), these inferred histories are highly prognostic! (1/9) doi.org/10.1101/2023.1…

In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK. “A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory

Me watching #thecurse last night: media3.giphy.com/media/l2SqanJX…

V happy catching up with another of my fav haematologists (& dear friend/collaborator) this wk, with Cris Lo Celso staying with us in Melb after receiving a highly deserved prize for her IVM contributions in Sydney on Friday! We enjoyed a trip to Healesville Sanctuary yesterday♥️

Tacos #ASH23 starts in a week in San Diego my home town! More important than the abstracts are the amazing tacos you must eat in this city. Here is a tweetorial where you must eat. Oscars in Pacific Beach (two locations right by beach) My personal favorite chorizo shrimp taco

On the way to #ASH23 Truly happy to have contributed this commentary in Blood with my mentor and incoming president of ASH Mohan Narla on the amazing work from Egan Lab Parasite hijacks red cell membrane proteins ashpublications.org/blood/article/…

Looking forward to #ASH23 . Very proud of Dr Hongwei Ren and Natalina Elliott who have worked on this Science and Innovation at Cancer Research UK funded project co-led by Prof Karadimitris Imperial Department of Immunology & Inflammation . Dr Ren has won an abstract achievement award 🙌, and will be presenting on Monday 👇

So grateful to the #TRTH, European Hematology Association and ASH for this fantastic year! Amazing mentors and fellows! Looking forward to what the future will bring to us! #TRTH2023 #ASH2023

If you look out for kind running mates at #ASH23 5(4.2)K, make sure to apply for ASH/EHA #TRTH Alexandra B. Veloso Mikko Myllymäki As a caveat, you might also get exposed to stellar mentoring by inspiring leaders in hematology. hematology.org/awards/career-…

Inspiring talk by the inimitable Dr Blanche Alter who trained under the very Louis Diamond (Scwachan Diamond and Diamond Blackfan) and has had patients at the centre of her research into inherited bone marrow failure syndromes DBAS UK SDSUKCharity.

From bench to bedside! Wonderful plenary #ASH23 from Pamela Ting, @novartis on new potential therapy for upregualtion of HbF in Sickle Cell Disease. Exciting times for this somwhat neglected clinical area Julie Makani Ralph Brown

What a brilliant team I have!!! Please come along & retweet! Ruben A. Mesa, MD Naveen Pemmaraju, MD Raajit Rampal, M.D.Ph.D. Aaron Gerds MD, MS Claire Harrison J.J. Kiladjian Prithviraj Bose Stephen Oh Lucia Masarova, MD Brandi Reeves Lindsay Rein Levine Cancer Wake Forest Baptist - Comprehensive Cancer Center Jyoti Nangalia Beth Psaila MRC WIMM

Great job Paul and Blood Cancer UK!

Mother's Day Bake: peanut butter and dark chocolate smores Ottolenghi

Congrats to my NIH NHLBI colleagues Dr. David J. Young, MD PhD Brynn B. Duncan, MD Cynthia Dunbar on publication of their trial using EPAG in #DBA in British Journal of Haematology! Unfortunately suboptimal response seen, likely driven by necessary dose reductions due to thrombocytosis. onlinelibrary.wiley.com/doi/10.1111/bj… #IBMFS

Morning everyone! Pleased to share a detailed protocol of our bone marrow organoid approach in Nature Protocols : nature.com/articles/s4159….

youtube.com/watch?v=s5lZed…

#AcademicChatter #AcademicX