New Covid variant means we have to be more careful! Reserve some KN95 masks in Centre County! Let's be safe together

We've been collecting contact data (including age-structured contact rates) since March 2020 and will continue to do so...if you're a modeler and need contact data for the US, let us know!

Excellent thread by Dr. Angela Rasmussen on the relationship between epidemic characteristics and immune-escape. Large epidemic => virus has lots of chances to find that one lucky immune-escape mutation, like the E484K that has appeared multiple times. However, sometimes ... 1/

Ferrous Ferris is making #Rust. Ferris prefers they/them pronouns.

#epitwitter, on the anniversary of CBS Evening News Marc Lipsitch letting >5M Americans know that a million people could die a couple comments on what we need to fix before next winter - comments here: bit.ly/3be0YEH original CBS here cbsnews.com/news/coronavir… 1/

Hello #epitwitter, some #noncovid results here on #malaria mass drug administration (MDA) and the potential risk for drug-resistance. Pre-print recently posted. 1/ biorxiv.org/content/10.110…

Hi #epitwitter, attack rates for Connecticut here, our first attempt at these calculations for CT. Thanks to Forrest W. Crawford Fuhan Yang Thu Tran Nathan Wikle. We estimate that 21.6% (95% CredInt: 20.6% - 23.1%) of CT residents have been infected by #SARSCoV2 through Feb 28 2021. 1/

Hi #epitwitter, sorry to pile on with bad news, but we're not as immune as we think, and it's not just #Omicron's immune escape. In southern New England, it turns out that ~27% of vaccines were given to previously infected individuals. Pre-print below. 1/ medrxiv.org/content/10.110…

Thx Thu Tran Nathan Wikle for putting this together so quickly & Fuhan Yang Forrest W. Crawford for helping put all the CT Public Health data together. Thx Rhode Island Department of Health Mass. Public Health CIDD Bill Hanage @BillHanage.bsky.social & @SACEMAdirector Tulio de Oliveira Darren Martin for making all the Omicron results available so early. 8/

Hi #epitwitter & thx Bill Hanage @BillHanage.bsky.social. Our work on estimating attack rates is now published in JAMA Network Open. Main msg: in early 2021 we shouldn't have been aiming vaccination coverage at an uncertain #herdimmunity threshold. Vaccinating everyone & faster is the better approach. 1/

The One Health Poultry Hub is hiring! Looking for a postdoc or a research assistant in epidemiology to assess the role of chicken prod intensification 🐔 in South/Southeast Asia on emerging zoonotic disease risks. VEEPH Find out more: jobs.rvc.ac.uk/Vacancy.aspx?r…

Had a blast building species distribution model for frogs in Australia, Costa Rica, and South Africa with Fuhan Yang Weiming Hu Emily Howerton Chiara Vanalli Great work, Sweet Frog!

Today, Johns Hopkins Bloomberg School of Public Health launched a free course on infectious disease transmission for public health practitioners. This course, taught by Emily S Gurley and Amy Wesolowski, focuses on transmission models and decision-making. publichealth.jhu.edu/2022/johns-hop…

BioBlitz is important y’all 🐸

Hi #epitwitter, how does drug-resistance evolve to combination therapies? For #malaria this is a critical question, as #artemisinin-based combination therapies (ACTs) are now used worldwide, and drug-res evolves to both the artemisinins and the non-artemisinin partner drugs 1/

Very excited to see this preprint out! In a study led by Fuhan Yang, along with Thu Tran, Emily Howerton, and Maciej F Boni, we projected future annual burden of #COVID19 and how mortality in particular can be reduced through #vaccination and treatment access. 1/3

Everything published just last week. Big congratulations and immense thanks to Nguyen Tran gaobo Ricardo Aguas Thu Tran Jennifer Gardy Gates Foundation NIH Arjen Dondorp, Chanaki Amaratunga, Nick White, Mehul Dhorda, and many others. 14/ nature.com/articles/s4146…

BMC Medicine Joe Servadio Maciej F Boni Thu Tran Emily Howerton Vaccine is still the most effective way reducing burden. Over 52-80% vaccine coverage is needed to reduce the mortality comparable to the burden of influenza. Treatment offers effective alternative in reducing severity in low-vaccine-coverage circumstances. 3/3

Hello #epitwitter and #malaria Twitter 🦟, the Boni Lab (Maciej F Boni) had a new manuscript published today concerning #artemisinin resistance published in Nature Medicine today, a short thread 🧵to summarize our findings... 1/n nature.com/articles/s4159…

In summary, if we stick to something like 50% vaccine coverage and 15% treatment coverage w #antivirals (this is where we were in late 2022) then we should expect >81,000 deaths per year from COVID in the US. Analyses now published in BMC Medicine. 4/ bmcmedicine.biomedcentral.com/articles/10.11…