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Really happy with our new story on the role of egr3 in heart development!!! Thomas Juan Felix_Gunawan 🏳️‍🌈 Giulia Boezio Shivam Govind Jha

#Transcriptionfactor egr3 transduces biomechanical forces into molecular signals regulating #heart valve development #zebrafish. Image & research by Agatha Ribeiro da Silva et al Thomas Juan Stainier Lab Max Planck Institute for Heart and Lung Research in Science Advances. Links & archive on bpod.org.uk/archive/2024/5…

I would apply for this…

New paper alert 📰 Mechanical forces remodel the cardiac extracellular matrix during zebrafish development Very excited to share the latest work by first authors Alessandra Gentile and Marga Albu together with @Stainierlab! Out in @devjournal journals.biologists.com/dev/article/15…

Issue 13 is complete! On the cover: zebrafish cardiac ECM labelled by Tg(ubb:ssNcan-GFP) & surface rendered in 3D using Imaris. Colors mark distinct cardiac regions: ventricle (purple), atrioventricular canal (yellow) & atrium (green). See Gentile et al. journals.biologists.com/dev/article/15…

Beyond thrilled to present our first (!) work The Francis Crick Institute! A tour de force by Toby Andrews et al combining imaging, solid morphometrics, theory, perturbations to show how a developing heart grows and scales up its morphological complexity to keep beating... biorxiv.org/content/10.110…

Our work on a therapeutic approach in the vascular disease CCM has just been published. Targeting the polycomb repressive complex 1 suppresses lesion formation in a murine CCM model: DOI: 10.1161/CIRCULATIONAHA.123.067438 NAVBO EVBO DZHK Germany Circulation

New paper alert 📰 Beyond excited to share the latest work from our lab by first author Dorothee Bornhorst at Nature Communications ! nature.com/articles/s4146… The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish

The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration biorxiv.org/cgi/content/sh… #biorxiv_molbio

Excited to share our latest efforts to try better understand how the cardiac endothelium instructs heart regeneration. This was only possible thanks to the tremendous effort of Zhenyu Wang and Armaan Mehra and a great group of co-authors

Excited to share our project on Gpnmb during heart regeneration. Fun project that started with the endothelium and science took us to our beloved macrophages. This project was only possible thanks to the tremendous efforts of Savita Gupta and a great group of coauthors

Very happy to share my PhD work on Gpnmb during cardiac regeneration in zebrafish🥳. Thanks @Ruben and Didier Stainier Lab for all the support and guidance. Please check it out👇🏻

Excited to see our paper Stainier Lab "The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration" being highlighted with a News & Views article! Thank you Nature Cardiovascular Research and Kazu Kikuchi! 😊 nature.com/articles/s4416…

Paper alert! Congrats to Lara, Christopher Dooley, Douglas Adamoski and Thomas Juan for their great work on identifying the first example of Transcriptional Adaption in humans!🎉