JCI insight
@JCI_insight
Publishing excellent science across all areas of biomedicine - find out more: https://t.co/sYZ1qJwZub
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http://insight.jci.org 07-10-2016 18:36:24
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Atrogin-1 promotes muscle homeostasis by regulating levels of endoplasmic reticulum chaperone BiP: buff.ly/4dcP0sQ
Dr Avnika Ruparelia Pete Currie Centre for Muscle Research
#MuscleBiology
In utero and postnatal ivacaftor/lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets: buff.ly/3w1q1Ip
Carver College of Medicine
#Pulmonology #Therapeutics
Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy: buff.ly/3JnnV8A
Thomas Jefferson University
#Genetics #Neuroscience
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART: buff.ly/3Josqjy
Shelli Farhadian Yale School of Medicine
#AIDS #HIV #Immunology
Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish: buff.ly/3Jg6nLP
Mayo Clinic
#Cardiology #Genetics
A urine-based test that detects tumor DNA fragments could offer early reliable screening for head and #neckCancer @umich @JCI_Insight medicalxpress.com/news/2024-04-u…
#ClinicalMedicine :
A complement C4–derived glycopeptide is a biomarker for PMM2-CDG: buff.ly/3VUV3w4
Akhilesh Pandey Lab Morava Eva Mayo Clinic Icahn School of Medicine at Mount Sinai
#Genetics #Metabolism
Alkali injury–induced pathological lymphangiogenesis in the iris facilitates the infiltration of T cells and ocular inflammation: buff.ly/3xCJboi
#Immunology #Ophthalmology
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS: buff.ly/4ayHPcZ
NIAID News
#ClinicalMedicine #AIDS #HIV
#ClinicalTrials
Activation of the IKK2/NF-κB pathway in VSMCs inhibits calcified vascular stiffness in CKD: buff.ly/49xft1f
CU Anschutz Medical Campus
#VascularBiology
Single-cell molecular signature of pathogenic T helper subsets in type 2–associated disorders in humans: buff.ly/43ZHo9a
Pedro Gazzinelli Guimaraes NIAID News
#Immunology #InfectiousDisease
Prophylactic efficacy of an intranasal spray with 2 synergetic antibodies neutralizing Omicron: buff.ly/4aqLbPd
#ClinicalMedicine
#COVID_19 #Immunology
Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment: buff.ly/3TPArml
UC San Francisco
#Immunology #Oncology
Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance: buff.ly/43UIOkX
Nadejda Bozadjieva Kramer, PhD Randy J. Seeley, Ph.D. Michigan Medicine
#Gastroenterology #Metabolism
Neutrophil proteases are protective against SARS-CoV-2 by degrading the spike protein and dampening virus-mediated inflammation: buff.ly/3vVffmN
Charaf Benarafa Universität Bern
#COVID_19 #Inflammation