Congratulations to Jon Anker, MD, PhD, Icahn School of Medicine at Mount Sinai, recipient of Bladder Cancer Advocacy Network Young Investigator Award. #bladdercancer

Happy to see our story on tolerance to inflammation antigens Nature Immunology nature.com/articles/s4159… It grew from a naive question I had at my first immunology class: if some self molecules are only induced by pathogen how does immune system distinguish them from foreign antigens?1/n

Have a look at our work showing how the hypoxic TME mechanistically shuts down NK cell function through SLAMF6 signaling.

Thank you Klebanoff_Lab Bhardwaj Lab Justin Eyquem Absolutely amazing discussions with an incredible group of scientists. Parker Institute for Cancer Immunotherapy

Amazing new study published in nature by Bob Schreiber’s group, first author Hussein Sultan. Great work on identifying a suppressive CD4 T cell population induced uniquely by high-dose long peptide neoantigen vaccine, but not by low-dose vaccine. Very interesting!

🚨An entire meeting dedicated to innovation and progress in solid tumor cell therapy!🚨 On behalf of my co-organizers and Society for Immunotherapy of Cancer, please save the date and spread the word! #ChristineBrown Jennifer Guerriero, PhD John Haanen Daniel Powell Lab @ UPENN Evan Weber #TIL #TCR #CAR #Synbio

Cool paper form Michael Lim, MD lab showing the cytokine Meteorin-like suppresses CD8 fxn in tumors via suppression of mitochondrial respiration #immunometabolism cell.com/immunity/fullt…

Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T cell exhaustion. Great work by Shin Ngiow and super collaboration (and 2 other great papers) with Vignali Lab and Dario Vignali cell.com/cell/abstract/…

Happy Friday 🍟 from the Bhardwaj Lab! No better way to end a busy week than to play shuffleboard and relax with our labmates. #SummerFridays

Elegant study of targeting cytokines to immune cells in the TME with amazing results in notoriously challenging tumor models. Impressive!

According to Michelle Alyssa Tran, PhD, “Through the first single-cell RNA sequencing of #BladderCancer patient urine, we find that urine contains a rich diversity of immune cells that transcriptionally mirror those found in bladder tumors!” x.com/michelle_a_tra…

Thank you NCI Division of Cancer Biology for funding our work & highlighting our study of urine as a window into the bladder tumor microenvironment!

Excited for #CICON24! From our lab, Theresa Chu, Guillaume Mestrallet and Jenna Newman, Ph.D. are attending and presenting posters. Today, please visit Theresa and Jenna’s posters on neoantigen-reactive T cells in B16F10 melanoma!

#CICON24 day 1 down! An energizing day filled with great science (TLS, bioinformatics, neoadjuvant therapies), amazing poster presentations, and socializing with our Sinai friends and beyond

Grateful for the opportunity to present a poster at my first ever conference! Thank you to everyone who stopped by and for their engaging conversations! Excited for the rest of the conference and hearing more about the groundbreaking research being done! #CICON24

Check out our new review by Mesude Bicak Cansu Cimen Bozkus on checkpoint blockade!

REVIEW Journal of Clinical Investigation Bhardwaj Lab Dr. Nina Bhardwaj Mesude Bicak Cansu Cimen Bozkus Checkpoint therapy in cancer treatment: progress, challenges, and future directions jci.org/articles/view/…

Our review on checkpoint therapy, now live bit.ly/3zzTtqx Journal of Clinical Investigation Cansu Cimen Bozkus Dr. Nina Bhardwaj Bhardwaj Lab The Tisch Cancer Institute Lipschultz Precision Immunology Institute Icahn School of Medicine at Mount Sinai