New paper out in Nature Neuroscience! Collaborating with several labs, we developed genetically encoded biosensors to track opioid pharmacology in the brain & provide powerful new tools for dissecting complex circuit-specific dynamics 🔧🧠 nature.com/articles/s4159…

Happy to have contributed to the development of novel endogenous opioid biosensors. Thank you Chunyang (Jason) Dong for being an amazing collaborator, Lin Tian, PhD for the opportunity, mbruchas for the guidance and NIDAnews for the funding!

New work out in Neuropsychopharmacology from Caitlin Orsini Alexa-Rae Wheeler & team highlighting a potential role for D2Rs (but not D1Rs or D3Rs) sensitivity in the basolateral amygdala in contributing to sex differences in risk-based decision-making in🐀 nature.com/articles/s4138…

jneurosci.org/content/44/30/… Mixed selectivity…in the auditory midbrain? @GArtofscience certainly says so. Additional shout out to the reviewers who provided some of the most constructive and eloquently written critiques of my career thus far.

Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit biorxiv.org/cgi/content/sh… #biorxiv_neursci

Position for computational chemist at RTI: nam12.safelinks.protection.outlook.com/?url=https%3A%… Please RT

Just dropped- a really epic work from @sciencejuls and Larry Zweiffel, finally uncovering the functions of the enigmatic nucleus-accumbens CRH cells in reward behaviors. Unsurprisingly, this peptide's actions remain, ahem, WEIRD. sciencedirect.com/science/articl…

Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability biorxiv.org/cgi/content/sh… #biorxiv_neursci

A dopamine-dependent mechanism for reward-induced modification of fear memories biorxiv.org/cgi/content/sh… #biorxiv_neursci

We're thrilled to share the lab's first preprint- on CRF neurons, hypocretin/orexin signaling, and BNST neurophysiology in excess alcohol drinking and withdrawal-enhanced anxiety behavior! A collaborative effort with Julie Kauer and Anne Vassalli, led by postdoc Dr. Yihe Ma

Our lab is looking for a motivated postdoc interested in dissecting the circuits of pain negative affect. More details about the lab here : massalylab.com & contact me here : massalylab.com/opportunities I will also be at #SfN24 in a couple of weeks to chat more.

Congrats to our very own Dr.ErinCalipari on the Jacob P. Waletzky Award from Society for Neuroscience (SfN) recognizing her work on addiction! Find out more about the award here: sfn.org/initiatives/aw…

Dopamine D2/3 receptor densities may underlie the functional architecture of cocaine use. @AvramHolmes; Jocelyn A. Ricard; Loïc Labache; Ashlea Segal; Elvisha Dhamala; Carrisa V Cocuzza, PhD (she/her); Sarah Yip; Sidhant Chopra doi.org/10.1038/s42003…

Very proud to have my first first author paper published today in Neuropsychopharmacology ! If you're interested in dopamine and cocaine incubation consider taking a look. nature.com/articles/s4138…

Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits biorxiv.org/content/10.110…

Striatal Serotonin Release Signals Reward Value jneurosci.org/content/44/41/… Congrats to Kate Nautiyal and team!! 👏👏

Amazing new work by Kate Nautiyal!

I’m excited to share the most recent study from the mbruchas lab, which represents the culmination of my postdoctoral work, and serves as the platform for my future research programs investigating the in vivo role of the endocannabinoid signaling system! biorxiv.org/content/10.110…

Please chk out the lab's newest paper, a labor of love it was. From Andrew Luskin & Li Li, MD, PhD, w/ @madisonmartin Brain in a jar Rhiana C Simon, PhD @GoldenNeuron Stuber Lab & others. We report a new road map for the LC-NE & peri-LC systems. Thx National Institute of Mental Health (NIMH) NIDAnews nature.com/articles/s4158…