Ryan Hoover Bobby Lee Lex Fridman We keep coming back to these words from Coach Mark Dantonio “treat compliments like a piece of gum -- they are meant to be spit out quickly after brief enjoyment.” On to the next.

🌶️take: ChatGPT o3 is too smart for its own good. Particularly for marketing and editing, it over-reasons. It holds too close to best practices, where 4o is more fluid, more willing to wing it with a bit of personality. OpenAI

The only real alpha in navigating complex systems is to figure out which steps can be skipped while maintaining or improving quality.

Exciting news - Vincere has teamed up with Beiersdorf, the company behind leading skin care brands like NIVEA and Eucerin, to develop mitophagy-enhancing molecules for anti-aging skin care! You can learn more and chat with the team at: linkedin.com/posts/vincere-…

The future is weird - and I'm here for it.

If you’re not running (or equivalent) 20 miles per week, NGMI.

I’ve kind of given up on X for a bit. Is X of today worthy of more of my attention?

Reminds me of a heated discussion with our wedding photographer almost 25 years ago around her position that “digital is not archival”. If you want to be remembered, syndicate your content to multiple platforms, including hard copy. Yes—I’m glad to have negatives in the vault.

Everything will converge upon instant, perfect, and free. Beyond that, who can predict the ripples?

Underrated.

If anyone is interested - I've integrated these letters into a GPT so you can chat with them: bit.ly/regulatory-co-…

Life is too short to do easy things.

Since understanding analog clocks is one of the first things to go in human dementia, this will be a very interesting benchmark to follow.

Do interesting things with interesting people.

I’ll take superhealth over superintelligence any day.

Even the loudest Bitcoin bulls are calling for $200K next year and maybe $1M someday. If 2-10× is the ceiling of your imagination, you need to rethink your ambition. That’s table stakes in private equity and company creation.

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Alpha today is in knowing what AI is good at, what it's not, and efficiently juggling to maximize human + computational capacity.

This is the foundation of clinical trial approvals in Infinita City Próspera What would it take for insurers to become the efficient regulators of the US too?