Two research teams (Rejuvenate Bio & David Sinclair) reverse signs of aging in mice science.org/content/articl…

Fellowships in Drug Discovery, Agricultural Science, and Medical Science. Apply from February 13th and become part of our #BFBoundaryBreakers! We support brilliant young scientists in life sciences with up to 10,000 € of #funding for up to 6 months abroad.

Get to know some of our #BFBoundaryBreakers and fellowship awardees from the last years by following this list: x.com/i/lists/138741…

More evidence of the normal physiological roles of cell senescence. In an invertebrate cnidarian, senescent cells can reprogram neighbouring somatic cells into stem cells and drive whole-body regeneration. Great work by Uri Frank et al Cell Reports! cell.com/cell-reports/f…

Excited to officially start my Ph.D. journey in Elly Tanaka’s lab IMP. My goal is to contribute to the field of high-throughput genetics in the axolotl, the only four-legged vertebrate that can regenerate virtually any body part and doesn’t show classical signs of aging.

We're introducing new PhD students that recently joined the Vienna BioCenter PhD program. Welcome to the VBC! A new call opens on 1 September, check out our website for details: training.vbc.ac.at/phd-program/ IMP IMBA imbavienna.bsky.social GMI Vienna gmivienna.bsky.social Max Perutz Labs Vienna Universität Wien MedUni Wien

Woohoo! 🎉 Just secured the 1st place in the 3MT competition at Cambridge!🥇Had an absolute blast at the LMB-IP Graduate Life Sciences Symposium, hosted by @MRC_LMB. Met fantastic people and made valuable connections—such a great start in my PhD! 💪 #Cambridge #3MT #Competition #PhDLife

.André Fischer from Uni Göttingen, MPI for Multidisciplinary Sciences joined the lab of Elly Tanaka Elly Tanaka at IMP to identify genetic dependencies of fibroblast reprogramming during axolotl limb regeneration using functional genomic screens.

Hypersensitive axolotl mTOR kinase orchestrates regeneration via translational priming and low abundant nutrient sensing in the wound microenvironment. Inhibiting amino acid uptake and subsequent axmTOR activation prevents wound healing! nature.com/articles/s4158…

Congrats to André Fischer for his newly acquired LMBee! 🐝 André presented his master's LMB-IP Graduate Life Sciences Symposium & won 1st place in the 3-min thesis competition ! He recently started his #PhD at the IMP, in the lab of Elly Tanaka (Elly Tanaka).

Could the unique #mTOR variant in #axolotls reverse #aging and promote #longevity? Our thoughts on our work from Barna Lab is profiled in a new highlight Nature Aging nature.com/articles/s4358…

A PCR-based method which can detect methylated DNA without any pre-treatment #BiotechNatureComms nature.com/articles/s4146…

Researchers in MIT Biology present evidence that the HIV-1 capsid mimics the cell's transport receptors to traverse the nuclear pore news.mit.edu/2024/capsid-hi…

What an excellent opportunity it was to experience such an international atmosphere and explore a different area of research that shaped my current PhD project! Thank you, Bayer Foundation, for making this possible.

Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency go.nature.com/3RYbPHK

New at IMBA: Paths to Regeneration (2024) by Ella Steinbacher, inspired by André Fischer. This painting captures an extraordinary natural process in axolotls, where adult somatic cells revert to a more versatile state, enabling regeneration.

Genuine epigenetic rejuvenation in primary cells has long been the holy grail. A groundbreaking preprint reveals that over-expression of a single (secret) gene overcomes this barrier: greatly reduced age estimates across in fibroblasts and keratinocytes according to validated