Nirogacestat undoubtedly is a great step forward in the tx of desmoid tumours, but: 1️⃣ is placebo the most appropriate control arm? 2️⃣ how long should the treatment last for? 3️⃣ can we safely recommend it to women of childbearing age? Looking forward to developing these answers!

Some good news! We recently received grants totalling £1 million to advance our translational research in #Sarcoma biomarkers, drug development & Omics The ICR. We are very grateful to Little Princess Trust Bone Cancer Research Trust Sarcoma UK Children’s Cancer and Leukaemia Group LifeArc for their generous support of our science!

Our new paper "The Proteomic Landscape of Soft Tissue Sarcomas" is out in Nature Communications! nature.com/articles/s4146… We characterise the proteomic profiles of >300 #sarcomas across 11 histological subtypes in paediatric & adult patients. What did we learn from this study? A 🧵1/n

I was watching Lord of the Rings last night and realized there are many parallels with academia! A thread 🧵👇

Let’s shake off the rust and get started #ESMO23 with the #GIST #educational symposium 🗓TODAY Oct 19, 10:15-11:45am 🗣 HALL 9, Santander auditorium 1️⃣ Localized and 1st line - Andrea Napolitano 2️⃣ IM-resistant disease - Sarah Watson 3️⃣ ctDNA & future - César Serrano

.Andrea Napolitano giving us updates on the latest clinical trials in #leiomyosarcoma Nice crossword puzzle!!😄

The clock is ticking for the 6th #Masterclass #Sarcomas organised by the Hellenic Group of Sarcomas and rare tumors with many invited speakers Jon Trent, MD, PhD Patrick Schöffski george demetri César Serrano García William Tap sylvie bonvalot Silvia Stacchiotti Emanuela Palmerini Javier Martin Broto hans gelderblom IOANNIS BOUKOVINAS

The accompanying Editorial: Centralisation of care improves overall survival for sarcoma patients annalsofoncology.org/article/S0923-… Robin Lewis Jones

I am beyond proud to have got a GOYIA by Conquer Cancer, the ASCO Foundation to support our research on HIV-associated HCC. This would have never been possible without the support of my team and my inspiring PI David James Pinato 🇺🇦 at Imperial College London ! Looking forward to generating new data for our patients!

Our new paper describing the Extracellular Matrix (ECM) networks in #Sarcoma is out in Clinical Cancer Research! We characterise the #extracellularmatrix and cell adhesion networks across >300 #sarcomas in 11 histological subtypes. What did we learn from this study? A🧵1/7

This impressive collaborative effort is finally out - Current Management of Desmoid Tumors: A Review | Pediatric Cancer | JAMA Oncology | JAMA Network ⁦Desmoid Tumor Research Foundation⁩ ⁦Desmoid Foundation ONLUS - Italia⁩ ⁦⁦CTOS⁩ ⁦SPAGN⁩ jamanetwork.com/journals/jamao…

We recently celebrated the 15 year anniversary of the Huang lab! 🥳🎉🎉 A MASSIVE thanks to all current and former lab members, mentors, colleagues & collaborators who have contributed to the successes of the lab. Here's to many more wonderful years to come! 🥂 The ICR