Many text books and publications state “#collagen is the most abundant protein making up 30% of total protein in mammals”. However, a direct measurement is missing. Here, we quantified total collagen of entire mice, which is 12-17%. biorxiv.org/content/10.110…

From Alban Longchamp, MD, PhD Exciting new research shows that increasing levels of the enzyme CGL, which produces proangiogenic gas H2S, can improve blood flow and neovascularization in models of PAD. #angiogenesis #peripheralarterialdisease

Stress rapidly increases your biological age, but this effect can be reversed if allowed time to recover. Duke MPI Jame White, Gladyshev Lab Read more in Cell Metabolism

The inability to preserve organs beyond several hours contributes to the scarcity of organs for transplantation. This Perspective reviews evidence for hypothermic machine perfusion & strategies to improve outcomes after transplantation bit.ly/CJASN0212 Alban Longchamp, MD, PhD

Learn more about the Legorreta Center for Clinical Transplant Tolerance at Mass General massgeneral.org/tolerance

The inability to preserve organs contributes to the scarcity of organs for transplantation. This Perspective reviews evidence for hypothermic kidney machine perfusion & future preservation/perfusion strategies to improve outcomes bit.ly/CJASN0212 Alban Longchamp, MD, PhD

Very excited to share the latest paper from our lab where we investigated the benefits of carbohydrate loading before surgery. nature.com/articles/s4146…. Big thanks and congrats to all of the authors & collaborators! @MikeMacArthur8 Ocampo Lab Kevin Kiesworo Arnaud Lyon Louis Stavart

Follow along as we post updates during our historic announcement at 10:00 a.m. ET. We'll be tweeting updates here, and you can also watch the announcement on this livestream: partners.zoom.us/j/81089940021

We are happy to share that today, Rick Slayman, our first patient to ever receive a genetically edited pig kidney transplant, has been discharged from the hospital. He is recovering well and will continue to recuperate at home with his family.

Learn more about our kidney #xenotransplant Mass General Transplant This short video provides an overview of the rationale, the details about the immunosuppression used, and the precautions taken in our study. Click on the second video in the video section @ leoriella.com

(1/3) Thrilled to have participated in Immunity's 30th anniversary cover contest. Many thanks to Kavitha Scranton for encouraging us to showcase our work, and congrats to 🥔! So grateful to be Prof Dela Golshayan and Dr Alban Longchamp, MD, PhD's MD-PhD student CHUV / Centre hospitalier universitaire vaudois Université de Lausanne!

onlinelibrary.wiley.com/doi/full/10.11…. Check out our paper evaluating static cold storage for GGTA1 KO kidneys before simulated xenotransplantation. Great work by the MGH Transplant Team! Leonardo V. Riella mohammadreza mojoudi

eGenesis lands $191m to advance xenotransplantation into clinical trials Company targets organ transplant shortage after world’s first successful transplant of genetically edited pig kidney into humans. #longevity #investment #kidney #transplant longevity.technology/news/egenesis-…

Merci Jennifer Covo ! rts.ch/play/tv/-/vide… via RTS

Check our last paper. Great team effort. Nicotinamide mononucleotide restores impaired metabolism, endothelial cell proliferation and angiogenesis in old se… pubmed.ncbi.nlm.nih.gov/39868046/

🚨 Breaking Records Again! 🚨 For 13 years in a row, our transplant teams have saved more lives through #OrganTransplantation than any hospital in New England. 👏 Shoutout to our patients, care teams and researchers for an amazing year in 2024! #TransplantInnovation #DonateLife

Amazing work from the entire MGH team! Groundbreaking. Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease | New England Journal of Medicine nejm.org/doi/full/10.10…

The story continues. Hope for so many patients : massgeneral.org/news/press-rel…

Association of Kidney Graft Long-term Outcome With... : Transplantation Direct journals.lww.com/transplantatio… . Congrats @Raffaella Emsley , Matthieu Stone Halfon, @Thomas Agius and many thanks to Dela Golshayan and the STCS team for the great collaboration.

Thrilled to share that I’ve joined the Massachusetts General Hospital as an Associate Surgeon in the Division of Transplantation, Department of Surgery. Grateful to my mentors, colleagues, and collaborators for their support, and excited to start this new chapter Mass General Surgery.