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A NEJM review on vitamins and micronutrients Table on the biomarkers below nejm.org/doi/full/10.10…

Very proud of my graduate students ⁦Adele Xu⁩ and Zijian Zhang & key members of our lab and collaborators ⁦⁦Garry P. Nolan⁩ & Sharon Pitteri lfor the incredibly hard work to characterize subcellular ribosomes. science.org/doi/10.1126/sc…

Don’t usually post sports on here, but what a game by UC San Diego Men’s Hoops so proud of their first NCAA D1 tournament appearance 🔱 Still remember going to their D2 games with ~100 people in audience. What a long way they’ve come!

Our new #preprint on NK cell engineering is out! biorxiv.org/content/10.110… Using #CRISPR activation screens, we found a programmable mechanism to mobilize NK cells to breast cancer tumors by engineering these cells to express orphan and metabolite-sensing receptors. (1/11) The

Excited to share ‘Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins’, by phenomenal superstar postdoc Aakriti Jain Aakriti Jain and amazing collaborators Rushika M. Perera, Guido Bommer, Charly Craik and James Olzmann: science.org/doi/10.1126/sc…

This is the most important paper in the circadian field in over a decade. A completely new clock component that is evolutionarily conserved. Erquan Zhang Susan Golden @ Society for Research on Biological Rhythms rdcu.be/efxV8

Metabolism (and horse) nerds: You have to check out this paper! Keap1 mutations in equine species permit increased Nrf2 activity and help explain why horses have such big, strong, oxygen consuming muscles 💪🏼🐴 The nature of the mutation is as provocative as the physiological

Targeting #GDF-15 in cancer: Recent, early-phase trials show positive effects on two very challenging aspects of cancer care — #immunotherapy response and #cachexia symptoms. Read the News & Views from Jayesh Desai & colleagues Peter Mac Cancer Centre nature.com/articles/s4159…

We are glad to present our exploration of aging, dietary restriction, genetics, and the microbiome, led by levlitichev, together with our collaborators The Jackson Laboratory and Calico, just published at Nature Microbiology. Major findings are the following: (1/8) nature.com/articles/s4156…

CRISPRai simultaneously activates and represses two genes in single cells go.nature.com/4apFU9q rdcu.be/efe0E

Mapping the circuit between hunger, the brain, and the immune response Science Immunology AgRP=brain Agouti-related peptide neurons; CCL2=chemokine ligand 2; SNS-sympathetic nervous system science.org/doi/10.1126/sc…

New Science Magazine Discovery of a mechanism for cancer cachexia (components of severe apathy, depression) explained by a neuroimmune circuit science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

Happy to share our recent review on design principles of gene circuits for longevity! sciencedirect.com/science/articl…

Look out for the Wei Lab!!! Amazing future ahead 🤩 So glad to witness and be part of your journey

Sharing our latest review on peptide hormones by Laetitia Coassolo Laetitia Voilquin-Coassolo and Amanda Wiggenhorn Amanda Wiggenhorn in Trends in Biochemical Sciences Trends in Biochemical Sciences Stanford Pathology Free full text: sciencedirect.com/science/articl…

In a new Science study, researchers describe a neural circuit underlying cachexia-related apathy in a mouse model of cancer. Learn more ⬇️ 📄: scim.ag/42KkEe6 #SciencePerspective: scim.ag/4lA4BqQ

A ketogenic diet halts malaria parasite growth go.nature.com/4mlb0Gy

Really excited to share this work with @conor_mccluneon on Taxol biosynthesis!! 🌲💊

PhDone! 👨‍🎓 Grateful for the guidance and support of Long Lab in my graduate studies. And thanks to Stanford Cancer Biology PhD Program Sarafan ChEM-H for being such wonderful communities at Stanford 🙏 Appreciate my family and friends for the support 💪

Thank you so much for your support, Jon!