Delighted our review "The path to venetoclax resistance is paved with mutations, metabolism, and more" Science Translational Medicine science.org/doi/10.1126/sc… Fantastic work by Graeme Sullivan Lyndsey Flanagan & Daniel Alencar Rodrigues Physiology RCSI @RCSI RCSI Research and Innovation

Looking for a post-doc position? We have an open computational role UCD Conway Institute UCD SBBS to work on dysregulated transcriptional networks and epigenomic regulators in acute myeloid leukemia. Further details here: ucd.ie/workatucd/jobs/ conwaychromatinlab.com Please RT

At the ❤️of the cell on 14 Feb! Up next week in #CLASS is recent arrival & #ConwayFellow Eric Conway Eric Conway (and Kenny Rogers fan?🎤🎶🎸) #epigenetic #cancerregulation

We are delighted to bring you the first in-person All-Ireland Chromatin Consortium Active Motif conference UCD Conway Institute on May 24th. This conference will focus on 'Chromatin and Transcription in Development and Disease'. Register below for this free event: tinyurl.com/2nszuye8 #AICC2023

Delighted to share our CBX7-JARID2 story now in Molecular Cell. To our surprise, Cheng Wang and I uncovered a new mode of PRC1 recruitment by JARID2! Amazing team effort as always, thanks Adrian Bracken lab and collaborators MVermeulenLab DPlab cell.com/molecular-cell…

Looking forward to this weeks (in person) seminar from Michael Keogh CSO of EpiCypher, Inc. taking place in UCD Conway Institute. Any and all nucleosome aficionados welcome to attend!

3 weeks left to apply for this PhD position on enhancer biology in AML, importantly with updated stipend €20,000 p.a 9 days left for applications for a postdoc focussed on the role of PAX8 in ovarian cancer. worldwidecancerresearch.org/what-we-do/our… Please share & RT UCD Conway Institute UCD SBBS

Great fun visiting St. Andrews national school in Curragha with Aisling Coughlan for #scienceweek2023 today. Lemon volcanoes, homemade lava lamps and vinegar & baking soda rockets hopefully inspired some new budding scientists! UCD Conway Institute RCSI

Join our Lung Cancer Awareness month webinar, with Dr. Catríóna Dowling, a lecturer & principal investigator in the Department of Medicine at RCSI Dr Dowling will discuss her research & its impact in the context of lung cancer in Ireland. Register now: brnw.ch/21wEsqT

Okay, now Norman has conspired to have his best friend tied up right next to the fire 🔥 🤷‍♂️

Delighted our review is online, thanks Natalie and eckmaslab . If like us you are interested in how bivalent chromatin may play a role in cancer, check it out! doi.org/10.1042/BST202…

For our March 22nd webinar we are very excited to host Ali Shilatifard Shilatifard Lab for his talk on 'Transcription elongation control and chromatin in developmental gene expression, ageing and disease'. Register here: tiny.cc/u8b4xz

Congratulations to Stephanie from the TTC lab presenting her research on Multiple Myeloma in collaboration with Siobhan Glavey IrishResearch #RCSIResearchday24

Save the date! Our 3rd annual symposium is coming up on May 22nd in Ollscoil na Gaillimhe | University of Galway. If you are interested in chromatin, epigenetics, transcription, histones, single-cell genomics and much more please join us. Free registration through this link: allirelandchromatinconsortium.org/symposium2024

Delighted to share my first, First-author paper from my Breakthrough Cancer Research funded PhD! We identified the novel combination of 5-azacytidine and venetoclax for the treatment of Multiple Myeloma, which was effective ex-vivo irrespective of cytogenetics. haematologica.org/article/view/h…

Congratulations Lyndsey Flanagan, Triona Ní Chonghaile and Siobhan Glavey. Delighted to have been able to contribute to this great paper!

Great weather (mostly!) for my first day in University College Dublin UCD Conway Institute as an Ad Astra Assistant Professor for UCD Medicine! PhD positions available starting this September for those interested in functional epigenomics coughlan-lab.com/home-1-1

Last week to register for our All-Ireland Chromatin Consortium in person symposium in Galway this May! Should be a super meeting for anyone interested in epigenomics, transcriptomics and chromatin. Registration deadline this Friday.

Computational and wet-lab PhD positions are open for applications at my lab UCD Conway Institute UCD Medicine to work on Science Foundation Ireland IrishResearch funded project on functional epigenomics strategies to identify multiple myeloma therapeutic targets. More info: coughlan-lab.com/team