An impressive trio of papers makes a strong case for platelet factor 4 (PF4) as the key to reducing inflammation and improving cognition in the aged brain model nature.com/articles/s4158… nature Villeda Lab UCSF School of Medicine @justsaysinmice

This is a super cool convergence of work coming out of the labs of Dena Dubal UC San Francisco and Tara Walker Queensland Brain Institute, UQ demonstrating that the same plate factor – PF4 – can rejuvenate cognition in the context of klotho, exercise and young blood! Nature Aging Nature Communications

Excited to share our work out now out in nature ! Villeda Lab UCSF Bakar Aging Research Institute @SCAgingBrain Platelet factors attenuate inflammation and rescue cognition in ageing | Nature nature.com/articles/s4158…

A protein involved in wound healing can improve learning and memory in ageing mice go.nature.com/47xwitb

The goal of science is reproducibility. Newly published stories out in nature, Nature Aging, and Nature Communications today show it's possible for researchers to independently come to the same conclusion, identifying PF4 as cognition enhancing blood factor 🧵1/4