One of the most pressing questions. How can we promote CART persistence? Another fascinating talk by Carl June #cart2025 #EBMT #EHA #CART_is_the_future

Still a long way to go for #CART in myeloid malignancies. Modified stem cells appear to be a step in the right direction. #CART2025 #theEBMT #EHA_hematology #CART_is_the_future

Tremendous sucess for #CART in paediatric ALL. Early relapse post allo still comprises an area of unmet need. #CART2025 #theEBMT #EHA_HEMATOLOGY #CART_is_the_future

CART or allograft in rrCLL? Many times allograft is not possible and even more times CART is not available!! Luckily, CART seams to work on CLL! #CART2025 #EHA_hematology #the_EBMT #CART_is_the_future

Ways to overcome CART failure #CART2025 #The_EBMT #EHA_hematology #CART_is_the_future

Possible mechanisms of CV toxicity with CART. May be off target off tumor is the most prominent? #CART25 #theEBMT #EHA_hematology #CART_is_the_future

CV mortality contributes to the NRM in CART. Certainly less prominent than infection but worths a reminder during counselling patients. #CART2025 #theEBMT #EHA_Hematology #CART_is_he_future

Inflammatory state at baseline as a predictor of CV complications. #CART2025 #theEBMT #EHA_hematology #CART_is_the_future

Dual targeting is a promising concept. Will targeting BCMA (beside CD19) be effective in relapsed NHL post CD19 CAR? Watch the space! #CART2025 #theEBMT #EHA_Hematology #CART_is_the_future

Other targets as CD22 for CD19 CAR exposed disease? #CART25 #theEBMT #EHA_Hematology #CART_is_the_future

Options for progression post CART? May be TCE? Another CAR? Or allograft? #CART25 #theEBMT #EHA_Hematology #CART_is_the_future

TCE in the CART pathway #CART25 #theEBMT #EHA_Hematology #CART_is_the_future

CD19 targeting through CART pathway? Probably a safe / effective strategy? More evidence is needed. #CART25 #theEBMT #EHA_Hematology #CART_is_the_future

Bendamustine, should be avoided if possible ahead of Apharesis. #CART25 #theEBMT #EHA_Hematology #CART_is_the_future

england.nhs.uk/long-read/acut… Christie has been rated the 3rd best acute trust in the UK. The highest on the list for cancer care in the UK, a testimony for Christie’s unrivallled patient care.

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