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In 1929, a 25-year-old doctor cut into his own arm and inserted a catheter into his heart. No permission, no supervision, just sheer defiance. He risked death to prove a theory no one believed. His insane gamble saved millions of lives. Here's his story:

Forssmann was just 25 years old when he made history. As an intern at a small hospital near Berlin, he had an idea: what if doctors could access the heart without surgery? It sounded impossible and his superiors dismissed him outright.

But he didn’t let that stop him and took matters into his own hands. He needed surgical tools and he also needed a test subject. So he convinced Nurse Gerda Ditzen to help, making her believe she would be the first human experiment.

But he had no intention of putting anyone else in harm’s way. Instead, at the last second, he strapped her to the operating table and then cut into his own arm.

With no supervision, no assistance, and no guarantee that he’d even survive, he injected a local anesthetic into the skin of his left elbow. He then made an incision and threaded a catheter into a vein in his arm.

Important findings, but worth noting that individually, major trials (from AFFIRM to FAIR-HF2) missed their primary endpoints. Pooling the data helps. I think it has to do with the definition and also the fact that we treat the consequence (ID) and not the underlying causes.

It is important that one's enthusiasm to popularise the concept of four pillars of therapy for #HF is not allowed to spill over beyond #HFrEF British Society for Heart Failure #theFword European Society of Cardiology #HFA #CardioTwitter Sheffield Hospitals Sheffield Uni - Clinical Medicine 🦠 💉 🫀💙🔬🩺

A wonderful few days in Amman, Jordan at the 19th International Conference of the Jordan Medical Society at the invitation of Prof Ghnaimat. With Abdallah Al-Mohammad Anna Olsson-Brown David Breen and others Royal College of Physicians of Edinburgh Welcome and hospitality, as always, exemplary.

Interesting though somewhat disappointing finding of the #FAIR_HF2_DZHK05 trial JAMA Cardiology Javed Butler Theresa McDonagh British Society for Heart Failure #theFword #CardioTwitter Ahmed Bennis Dr.Rajiv Sankaranarayanan #Paul_Kalra doi.org/10.1001/jama.2…

Great talks on TAVI today from the Sheffield TAVI team. #CardioEd #cardioX #cardiotwitter

One of the best congresses is starting soon in Belgrade European Society of Cardiology #HFA2025 British Society for Heart Failure #theFword #CardioTwitter Mark Petrie Theresa McDonagh Andrew Clark

Excellent trials' sessions in Room 1 European Society of Cardiology #hfa2025 yesterday Javed Butler #Thomas_Greene Dr Klaus Witte MD #Brenda_Moura Adriaan Voors Amr Abdin EJHF Editor-in-Chief #J_Cleland HFAPresident British Society for Heart Failure #theFword #DrStefan_Anker #CardioTwitter

Another fruitful day European Society of Cardiology #hfa2025 HFAPresident Javed Butler scottdavidsolomon #Roy_S_Gardner Mark Petrie Ahmed Bennis #John_McMurray #CardioTwitter

#GDMT has now arrived for #HFpEF #SGLT2i (class I) and #nsMRA (class IIa) recommendations in initial global guidelines jstage.jst.go.jp/article/circj/… #HeartFailure2025

I was thrilled to have had the opportunity to attend European Society of Cardiology #HFA2025 in Belgrade. Excellent learning opportunities, good science, and an excellent opportunity to catch up with friends and colleagues British Society for Heart Failure #theFword HFAPresident European Society of Cardiology News #cardiotwitter

Excellent presentation by Safia Chatur, MD European Society of Cardiology #HFA post-hoc study of #FineArts_HF trial, looking at the impact of Finerenone on the patient's renal function as classified according to basic eGFR Muthu Vaduganathan scottdavidsolomon #John_McMurray #Pardeep_Jhund #CardioTwitter

This was one of my first ever publications after medical school. I'd never have imagined that 16 years later I'd be senior author on my own equivalent book due out this August. Can't wait for this! Akshay Gaur Mark Mills Abdallah Al-Mohammad

David Warriner Akshay Gaur Abdallah Al-Mohammad #EssentialECG